ELIZA

return kwic search for use out of >500 occurrences
821596 occurrences (No.5 in the rank) during 5 years in the PubMed. [no cache] 500 found

343) The purpose of this article is to perform an update and critical review about the biological basis of platelet-rich plasma, to review indications for which there is more scientific support on its use, and finally to describe their new indications that are currently under research.

--- ABSTRACT ---

PMID:23461926 DOI:10.1177/1753193413481937

2015 Cirugia y cirujanos

* [Platelets-rich plasma: a versatile tool for regenerative medicine?].

- Platelet-rich plasma is a blood product concentrate obtained by centrifugation of whole blood that is characterized by a high concentration of platelets (4 to 6 times their normal values). The high concentration of trophic factors contained in the granules of platelets, have led to suggest that the application of platelet-rich plasma can help to stimulate or accelerate the repair or regeneration of a number of tissues. Since their first application in the treatment of skin ulcers in 1980, a considerable number of novel applications in different fields of medicine have emerged (Ophthalmology, Otorhinolaryngology, Maxillofacial Surgery surgical wounds, musculoskeletal disorders, burns, Esthetic Surgery, repair of peripheral nerves, etc.), some of these applications with clearly positive or very promising results. Despite the large amount of experimental and clinical literature about the usefulness of platelet-rich plasma in different areas of regenerative medicine, there are few therapeutic indications in which it is fully demonstrated its effectiveness. This fact highlights the importance of carry out methodologically appropriate clinical trials in the near future, in order to improve the evidence level of platelet-rich plasma treatment. The purpose of this article is to perform an update and critical review about the biological basis of platelet-rich plasma, to review indications for which there is more scientific support on its use, and finally to describe their new indications that are currently under research.

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(1)263 of	(8)5 is	(15)3 by	(22)2 at
(2)34 in	(9)5 was	(16)3 it	(23)2 has
(3)24 null	(10)5 with	(17)3 these	(24)2 therapeutic
(4)24 and	(11)4 a	(18)3 were	(25)2 to
(5)8 the	(12)4 among	(19)3 when	(26)2 visual
(6)5 as	(13)3 are	(20)2 TAA
(7)5 for	(14)3 because	(21)2 acculturation,

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--- WordNet output for use --- =>利用, 使う, 利用する, (体, 能力など)を働かす, 使用, 利用法 Overview of noun use The noun use has 7 senses (first 6 from tagged texts) 1. (90) use, usage, utilization, utilisation, employment, exercise -- (the act of using; "he warned against the use of narcotic drugs"; "skilled in the utilization of computers") 2. (18) function, purpose, role, use -- (what something is used for; "the function of an auger is to bore holes"; "ballet is beautiful but what use is it?") 3. (7) use -- (a particular service; "he put his knowledge to good use"; "patrons have their uses") 4. (1) consumption, economic consumption, usance, use, use of goods and services -- ((economics) the utilization of economic goods to satisfy needs or in manufacturing; "the consumption of energy has increased steadily") 5. (1) habit, use -- ((psychology) an automatic pattern of behavior in reaction to a specific situation; may be inherited or acquired through frequent repetition; "owls have nocturnal habits"; "she had a habit twirling the ends of her hair"; "long use had hardened him to it") 6. (1) manipulation, use -- (exerting shrewd or devious influence especially for one's own advantage; "his manipulation of his friends was scandalous") 7. use, enjoyment -- ((law) the exercise of the legal right to enjoy the benefits of owning property; "we were given the use of his boat") Overview of verb use The verb use has 6 senses (first 3 from tagged texts) 1. (603) use, utilize, utilise, apply, employ -- (put into service; make work or employ for a particular purpose or for its inherent or natural purpose; "use your head!"; "we only use Spanish at home"; "I can't use this tool"; "Apply a magnetic field here"; "This thinking was applied to many projects"; "How do you utilize this tool?"; "I apply this rule to get good results"; "use the plastic bags to store the food"; "He doesn't know how to use a computer") 2. (12) use, habituate -- (take or consume (regularly or habitually); "She uses drugs rarely") 3. (8) use, expend -- (use up, consume fully; "The legislature expended its time on school questions") 4. use -- (seek or achieve an end by using to one's advantage; "She uses her influential friends to get jobs"; "The president's wife used her good connections") 5. practice, apply, use -- (avail oneself to; "apply a principle"; "practice a religion"; "use care when going down the stairs"; "use your common sense"; "practice non-violent resistance") 6. use -- (habitually do something (use only in the past tense); "She used to call her mother every week but now she calls only occasionally"; "I used to get sick when I ate in that dining hall"; "They used to vacation in the Bahamas") --- WordNet end ---