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- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for under out of >500 occurrences
321496 occurrences (No.66 in the rank) during 5 years in the PubMed. [no cache] 500 found
6) Under the stimulus of progesterone, this meiotic arrest is released and meiosis progresses to metaphase II, a process known as oocyte maturation.
--- ABSTRACT ---
PMID:24522008 DOI:10.1017/S0967199413000695
2015 Zygote (Cambridge, England)
* Effect of different types of sesquiterpene lactones on the maturation of Rhinella arenarum oocytes.
- The sesquiterpene lactones (STLs) are a large class of plant secondary metabolites that are generally found in the Asteraceae family and that have high diversity with respect to chemical structure as well as biological activity. STLs have been classified into different groups, such as guaianolides, germacranolides, and melampolides etc., based on their carboxylic skeleton. In amphibians, fully grown ovarian oocytes are arrested at the beginning of meiosis I. Under the stimulus of progesterone, this meiotic arrest is released and meiosis progresses to metaphase II, a process known as oocyte maturation. The purpose of this work was to determine whether sesquiterpene lactones from the germacranolide and melampolide groups act as inhibitor agents on the meiosis of amphibian oocytes in vitro. Results for germacranolides indicated that the addition of deoxyelephantopins caused a high degree of inhibition and that minimolide showed a moderate inhibitory effect, whereas glaucolide A was inactive. Furthermore, the addition of melampolides (uvedalin, enhydrin, polymatin A and polymatin B) showed inhibitory effects. For enhydrin and uvedalin, inhibitory effects were observed at the higher concentrations assayed. The results of this study suggest that the inhibitory activity of the tested sesquiterpene lactones on the meiosis of Rhinella arenarum oocytes is not dependent on the group to which they belong, i.e. not on the carboxylic skeleton, but probably due to the arrangement and type of function groups present in the molecules. All assayed lactones in the germacranolide group showed low toxicity. In contrast, important differences in toxicity were observed for lactones from the melampolide group: enhydrin and uvedalin showed low toxicity, but polymatin A and B were highly toxic.
--- ABSTRACT END ---
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(1)95 the (18)4 these (35)2 axial (52)2 of
(2)13 different (19)3 high (36)2 censoring (53)2 optimal
(3)12 a (20)3 investigation (37)2 clinical (54)2 physiological
(4)9 general (21)3 light (38)2 consideration (55)2 pulsatile
(5)8 both (22)3 local (39)2 controlled (56)2 scanning
(6)8 which (23)3 mechanical (40)2 current (57)2 serum-free
(7)7 various (24)2 *null* (41)2 evaluation (58)2 several
(8)6 conditions (25)2 12 (42)2 ex (59)2 simulated
(9)6 curve (26)2 15 (43)2 extreme (60)2 specific
(10)6 static (27)2 2 (44)2 four (61)2 steady-state
(11)5 and (28)2 CA (45)2 hypertensive (62)2 therapy
(12)4 5 (29)2 CT (46)2 hypoxia (63)2 this
(13)4 certain (30)2 H2O2-induced (47)2 hypoxic (64)2 time
(14)4 control (31)2 UV (48)2 inflammatory (65)2 treatment
(15)4 either (32)2 acute (49)2 laser (66)2 ultrasound
(16)4 in (33)2 additive (50)2 lateral (67)2 vertical
(17)4 normal (34)2 adverse (51)2 mortality (68)2 water

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--- WordNet output for under --- =>以下の, (治療, 試練, 刑罰)を受けて, 下部の, の下に, ・・の下に Overview of adj under The adj under has 2 senses (first 2 from tagged texts) 1. (2) nether, under -- (located below or beneath something else; "nether garments"; "the under parts of a machine") 2. (1) under -- (lower in rank, power, or authority; "an under secretary") Overview of adv under The adv under has 8 senses (first 1 from tagged texts) 1. (2) under -- (down to defeat, death, or ruin; "their competitors went under") 2. under -- (through a range downward; "children six and under will be admitted free") 3. under -- (into unconsciousness; "this will put the patient under") 4. under -- (in or into a state of subordination or subjugation; "we must keep our disappointment under") 5. under -- (below some quantity or limit; "fifty dollars or under") 6. under -- (below the horizon; "the sun went under") 7. under -- (down below; "get under quickly!") 8. under, below -- (further down; "see under for further discussion") --- WordNet end ---