160) In the performed receiver-operating characteristic curve analysis, area under curve (AUC) = 0.849 and P < .001 were detected for NLR > 1.84. |
PMID:23814171 DOI:10.1177/1076029613494469 |
2015 Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis |
* The role of the nonspecific inflammatory markers in determining the anatomic extent of venous thromboembolism. |
- We aimed to investigate the relationship between the extent of venous thromboembolism (VTE) and nonspecific inflammatory markers such as neutrophil to lymphocyte ratio (NLR) and high-sensitivity C-reactive protein (hs-CRP). We retrospectively enrolled 77 patients with VTE (distal deep vein thrombosis [DVT], n = 19; proximal DVT, n = 32; and pulmonary thromboembolism [PTE], n = 26) and 34 healthy controls. In the performed analysis of variance, the levels of white blood cell, NLR, and hs-CRP were clearly different among the groups (control, distal and proximal DVT, and PTE) (P < .001). Especially, a significant increase from the control group to the DVT and PTE was observed in the analysis made for NLR. In the performed receiver-operating characteristic curve analysis, area under curve (AUC) = 0.849 and P < .001 were detected for NLR > 1.84. For this value, the sensitivity and specificity were determined as 88.2% and 67.6%, respectively. The NLR is an inexpensive and a readily available marker that may be effective in determining the extent of VTE, and it is useful for risk stratification in patients with VTE. |
(1)95 the | (18)4 these | (35)2 axial | (52)2 of |
(2)13 different | (19)3 high | (36)2 censoring | (53)2 optimal |
(3)12 a | (20)3 investigation | (37)2 clinical | (54)2 physiological |
(4)9 general | (21)3 light | (38)2 consideration | (55)2 pulsatile |
(5)8 both | (22)3 local | (39)2 controlled | (56)2 scanning |
(6)8 which | (23)3 mechanical | (40)2 current | (57)2 serum-free |
(7)7 various | (24)2 *null* | (41)2 evaluation | (58)2 several |
(8)6 conditions | (25)2 12 | (42)2 ex | (59)2 simulated |
(9)6 curve | (26)2 15 | (43)2 extreme | (60)2 specific |
(10)6 static | (27)2 2 | (44)2 four | (61)2 steady-state |
(11)5 and | (28)2 CA | (45)2 hypertensive | (62)2 therapy |
(12)4 5 | (29)2 CT | (46)2 hypoxia | (63)2 this |
(13)4 certain | (30)2 H2O2-induced | (47)2 hypoxic | (64)2 time |
(14)4 control | (31)2 UV | (48)2 inflammatory | (65)2 treatment |
(15)4 either | (32)2 acute | (49)2 laser | (66)2 ultrasound |
(16)4 in | (33)2 additive | (50)2 lateral | (67)2 vertical |
(17)4 normal | (34)2 adverse | (51)2 mortality | (68)2 water |
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