ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for study, out of >500 occurrences
300943 occurrences (No.75 in the rank) during 5 years in the PubMed. [cache]
25) In this study, we assessed genetic variability and genetic structure of E.
--- ABSTRACT ---
PMID:24117184 DOI:10.3109/19401736.2013.840590
2015 Mitochondrial DNA
* Genetic variability of Echinococcus granulosus based on the mitochondrial 16S ribosomal RNA gene.
- Echinococcus granulosus is the etiological agent of cystic echinococcosis, a major zoonotic disease of both humans and animals. In this study, we assessed genetic variability and genetic structure of E. granulosus in the Tibet plateau, using the complete mitochondrial 16 S ribosomal RNA gene for the first time. We collected and sequenced 62 isolates of E. granulosus from 3 populations in the Tibet plateau. A BLAST analysis indicated that 61 isolates belonged to E. granulosus sensu stricto (genotypes G1-G3), while one isolate belonged to E. canadensis (genotype G6). We detected 16 haplotypes with a haplotype network revealing a star-like expansion, with the most common haplotype occupying the center of the network. Haplotype diversity and nucleotide diversity were low, while negative values were observed for Tajima's D and Fu's Fs. AMOVA results and Fst values revealed that the three geographic populations were not genetically differentiated. Our results suggest that a population bottleneck or population expansion has occurred in the past, and that this explains the low genetic variability of E. granulosus in the Tibet Plateau.
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(1)219 we (6)6 two (11)3 to (16)2 human
(2)85 the (7)4 which (12)2 24 (17)2 in
(3)22 a (8)3 DNA (13)2 an (18)2 serum
(4)11 and (9)3 therefore, (14)2 effects (19)2 six
(5)8 it (10)3 three (15)2 further

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--- WordNet output for study, --- --- WordNet end ---