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279736 occurrences (No.90 in the rank) during 5 years in the PubMed. [cache]
157) Patient-specific computational fluid dynamics (CFD) modelling of the left ventricle (LV) is a promising technique for the visualisation of ventricular flow patterns throughout a cardiac cycle.
2015 Computer methods in biomechanics and biomedical engineering
* A semi-automated method for patient-specific computational flow modelling of left ventricles.
- Patient-specific computational fluid dynamics (CFD) modelling of the left ventricle (LV) is a promising technique for the visualisation of ventricular flow patterns throughout a cardiac cycle. While significant progress has been made in improving the physiological quality of such simulations, the methodologies involved for several key steps remain significantly operator-dependent to this day. This dependency limits both the efficiency of the process as well as the consistency of CFD results due to the labour-intensive nature of current methods as well as operator introduced uncertainties in the modelling process. In order to mitigate this dependency, we propose a semi-automated method for patient-specific computational flow modelling of the LV. Using magnetic resonance imaging derived coarse geometry data of a patient's LV endocardium shape throughout a cardiac cycle, we then proceed to refine the geometry to eliminate rough edges before reconstructing meshes for all time frames and finally numerically solving for the intra-ventricular flow. Using a sample of patient-specific volunteer data, we demonstrate that our semi-automated, minimal operator involvement approach is capable of yielding CFD results of the LV that are comparable to other clinically validated LV flow models in the literature.
=>特有の, 特効薬, 明確な, 特定の, 種の, はっきりした
Overview of noun specific
The noun specific has 2 senses (no senses from tagged texts)
1. particular, specific -- (a fact about some part (as opposed to general); "he always reasons from
the particular to the general")
2. specific -- (a medicine that has a mitigating effect on a specific disease; "quinine is a
specific for malaria")
Overview of adj specific
The adj specific has 4 senses (first 2 from tagged texts)
1. (39) specific -- ((sometimes followed by `to') applying to or characterized by or distinguishing
something particular or special or unique; "rules with specific application"; "demands specific to
the job"; "a specific and detailed account of the accident")
2. (5) specific -- (stated explicitly or in detail; "needed a specific amount")
3. specific -- (relating to or distinguishing or constituting a taxonomic species; "specific
characters")
4. specific -- (being or affecting a disease produced by a particular microorganism or condition;
used also of stains or dyes used in making microscope slides; "quinine is highly specific for
malaria"; "a specific remedy"; "a specific stain is one having a specific affinity for particular
structural elements")
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