ELIZA

return kwic search for significantly out of >500 occurrences
583352 occurrences (No.14 in the rank) during 5 years in the PubMed. [cache]

173) By day 7, PBL was significantly reduced (p < 0.05), with significantly reduced inflammation (p < 0.05) and gingival hyperplasia (p < 0.001), in the animals receiving three irradiations per week.

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PMID:23933707 DOI:10.1007/s10103-013-1416-0

2015 Lasers in medical science

* Controlling periodontal bone levels with multiple LED irradiations.

- Because a single exposure to light-emitting diode (LED) irradiation at 660 nm only demonstrated a 3-day biostimulatory effect in recovering periodontal bone level (PBL), this study sought to evaluate whether the periodontal effect could be extended through the use of multiple LED irradiations. Experimental periodontitis was developed unilaterally in 48 Sprague-Dawley rats after the placement of a silk ligature plus Porphyromonas gingivalis lipopolysaccharide injections. The animals were divided into four groups (no irradiation, a single irradiation, or two or three irradiations per week) and exposed to LED light irradiation at a wavelength of 660 ± 25 nm and energy density of 10 J/cm(2) after debridement and detoxification. The animals were euthanized after 7 or 14 days, and the effect of irradiation was evaluated using micro-computed tomography and histology. By day 7, PBL was significantly reduced (p < 0.05), with significantly reduced inflammation (p < 0.05) and gingival hyperplasia (p < 0.001), in the animals receiving three irradiations per week. At day 14, the reduction in gingival hyperplasia was still significant (p < 0.05), and collagen matrix deposition and realignment appeared to be accelerated in the animals receiving three irradiations per week, despite a lack of significant difference in PBL. The treatment regimen receiving three LED light irradiations per week apparently extended the effects in reducing PBL and inflammation to 7 days. The inclusion of additional inflammation control measures or the addition of bioactive signals to mediate the repairing process is necessary to maintain long-term periodontal stability.

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[frequency of next (right) word to significantly]

(1)88 higher	(13)8 improved	(25)3 (P<0.05)	(39)2 impaired
(2)43 lower	(14)6 correlated	(27)3 affect	(40)2 increases
(3)39 increased	(15)6 elevated	(28)3 better	(41)2 induced
(4)35 reduced	(16)6 fewer	(29)3 increase	(42)2 larger
(5)32 associated	(17)6 less	(30)3 worse	(43)2 predicted
(6)17 decreased	(18)5 enhanced	(31)2 (P	(44)2 reduce
(7)13 in	(19)5 inhibited	(32)2 (p	(45)2 shorter
(8)13 more	(20)4 affected	(34)2 altered	(46)2 smaller
(9)10 greater	(21)4 attenuated	(35)2 by	(47)2 suppressed
(10)10 related	(22)4 between	(36)2 compared	(48)2 to
(11)9 null	(23)4 from	(37)2 decreased,
(12)9 different	(24)4 the	(38)2 differed

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--- WordNet output for significantly --- =>きわめて, 意味深く, 意味ありげに Overview of adv significantly The adv significantly has 3 senses (first 2 from tagged texts) 1. (6) significantly -- (in a statistically significant way; "the two groups differed significantly") 2. (3) significantly -- (in a significant manner; "our budget will be significantly affected by these new cuts") 3. importantly, significantly -- (in an important way or to an important degree; "more importantly, Weber held that the manifold meaning attached to the event by the social scientist could alter his definition of the concrete event itself") --- WordNet end ---