kwic
significant
significant
right
off
ON
72
1
100
500
strict
ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -
return
kwic search for significant out of >500 occurrences
583352 occurrences (No.14 in the rank) during 5 years in the PubMed. [no cache] 500 found
--- ABSTRACT ---
--- ABSTRACT END ---
[frequency of next (right) word to significant]
583352 occurrences (No.14 in the rank) during 5 years in the PubMed. [no cache] 500 found
| 72) The analysis of plasma sex steroid levels revealed a significant increase in 17β-estradiol and testosterone in plasma of juvenile males and females, respectively. |
| PMID:23771873 DOI:10.1177/0748233713491806 |
| 2015 Toxicology and industrial health |
| * Short-term responses of selected endocrine parameters in juvenile rainbow trout (Oncorhynchus mykiss) exposed to 4-nonylphenol. |
| - The synthetic organic compound 4-nonylphenol (4-NP) has been shown to have a wide range of adverse effects on the endocrine system of various animals including fish. The present study evaluated the potential effects of 4-NP on vitellogenin (VTG) synthesis, steroid, and thyroid hormone concentrations in both juvenile male and female rainbow trout (Oncorhynchus mykiss). Fish were exposed by intraperitoneal injection to different doses of 4-NP (1, 10, 50, and 100 μg g(-1)) or vehicle (coconut oil) over a period of 14 days. Blood samples were collected 7 and 14 days after initiation of treatment. Plasma VTG levels in 4-NP-treated fish were detected by sodium dodecyl sulfate polyacrylamide gel electrophoresis as a high molecular weight protein band of 180 KDa. In addition, plasma VTG concentrations were quantified indirectly using plasma alkali-labile phosphate (ALP) and plasma calcium. Both ALP and calcium levels in plasma showed similar and parallel increase patterns after exposure to 4-NP that were significantly higher compared with controls. The analysis of plasma sex steroid levels revealed a significant increase in 17β-estradiol and testosterone in plasma of juvenile males and females, respectively. Furthermore, a significant increase was observed in plasma cortisol levels. On the other hand, 4-NP decreased both plasma triiodothyronine and thyroxine after 7 and 14 days of treatment. These results suggest that 4-NP can affect different parts of the endocrine system, which may lead to serious impairments in physiological homeostasis of juvenile rainbow trout. |
[
right
kwic]
(1)67  differences |
(15)5 correlations |
(29)3 influence |
(44)2 dose-dependent |
| (2)40 increase |
(16)5 effects |
(30)3 negative |
(45)2 elevation |
| (3)36 difference |
(17)5 for |
(31)3 number |
(46)2 evidence |
| (4)28 decrease |
(18)5 increases |
(32)3 roles |
(47)2 factors |
| (5)12 reduction |
(19)5 risk |
(33)2 (P |
(48)2 group |
| (6)11 predictors |
(20)4 effect |
(35)2 alterations |
(49)2 inhibition |
| (7)10 association |
(21)4 in |
(36)2 and |
(50)2 interaction |
| (8)9 improvement |
(22)4 reductions |
(37)2 at |
(51)2 morbidity |
| (9)8 *null* | (23)4 relationship |
(38)2 between-group |
(52)2 positive |
| (10)7 changes |
(24)3 (p |
(39)2 blood |
(53)2 prediction |
| (11)7 predictor |
(25)3 alteration |
(40)2 challenge |
(54)2 proportion |
| (12)7 role |
(26)3 as |
(41)2 contribution |
(55)2 source |
| (13)6 correlation |
(27)3 higher |
(42)2 cytotoxic |
(56)2 time |
| (14)5 associations |
(28)3 improvements |
(43)2 decreases |
add keyword
--- WordNet output for significant ---