* Risk factors during the prenatal period and the first year of life associated with overweight in 7-year-old low-income Chilean children.
- The objective of this study was to identify in low-income Chilean children with normal birthweight which factors occurring during the prenatal period and the first year are associated with overweight (OW)/obesity at 7 years. The sample included 652 7-year-olds from a larger cohort study. We collected anthropometric data at 0, 12 and 84 months, maternal pre-pregnancy and pregnancy characteristics, early feeding practices, number of siblings, birth order, breastfeeding, and timing of solid introduction information. We determined the residuals for z-scores for body mass index (BMI) (BAZ), weight/age and height/age0-12 months , run univariate analysis (X(2) or t-test) and multivariate logistic analyses (stepwise approach); P < 0.05 was considered significant. We evaluated the goodness of fit of the model using the Hosmer-Lemeshow test and checked for overdispersion using the Pearson's X(2) . The odds of children being OW at 7 years increased if their mothers were OW before pregnancy, if born with a higher BAZ (increase of 18-74% per each additional unit of BAZ) and if their BAZ growth during the first year was higher (62-239% per each unit over the predicted BAZ increase). Higher birth order was protective (6-68% less risk for 2nd birth compared with 1st and 10-73% less for ≥3rd child). All other variables, including gender, were non-significant (P > 0.1). In low-income Chilean children with normal birth, four factors during the prenatal period and the first year were associated with OW at 7 years: pre-pregnancy BMI, BMI at birth, BMI gain between 0 and 12 months, and birth order.
=>意義深い, 重大な, 意味のある, 意味ありげな, 重要な
Overview of adj significant
The adj significant has 4 senses (first 4 from tagged texts)
1. (18) significant, important -- (important in effect or meaning; "a significant change in tax
laws"; "a significant change in the Constitution"; "a significant contribution"; "significant
details"; "statistically significant")
2. (9) significant, substantial -- (fairly large; "won by a substantial margin")
3. (3) significant -- (too closely correlated to be attributed to chance and therefore indicating a
systematic relation; "the interaction effect is significant at the .01 level"; "no significant
difference was found")
4. (2) meaning, pregnant, significant -- (rich in significance or implication; "a meaning look")
--- WordNet end ---
PubMed database: last updated on 2020-12-01 (c)sirasawa 2019