ELIZA

return kwic search for significant out of >500 occurrences
583352 occurrences (No.14 in the rank) during 5 years in the PubMed. [no cache] 500 found

265) On multivariate analysis, only immunophenotype remained significant for progression-free survival (PFS), whereas no variables remained significant for ST.

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PMID:23786518 DOI:10.1111/vco.12045

2015 Veterinary and comparative oncology

* Prognostic value of baseline absolute lymphocyte concentration and neutrophil/lymphocyte ratio in dogs with newly diagnosed multi-centric lymphoma.

- Canine multi-centric B-cell lymphoma shares similarities with diffuse large B-cell (Non-Hodgkin's) lymphoma (NHL) in people. In people with NHL, lymphopenia at diagnosis and first relapse and neutrophil/lymphocyte ratio (N:L) > 3.5 are negative prognostic factors for survival. The objective of this study was to determine if lymphocyte concentration at diagnosis and first relapse and N:L were prognostic for survival in dogs with newly diagnosed multi-centric lymphoma. Medical records of 77 dogs with multi-centric lymphoma treated with a CHOP-based chemotherapy protocol were retrospectively evaluated. Absolute lymphocyte concentration and N:L ratio at presentation of dogs pre-treated with steroids was not significantly different from dogs who had not received steroids. On multivariate analysis, only immunophenotype remained significant for progression-free survival (PFS), whereas no variables remained significant for ST. A prospective study of these haematologic variables is warranted to assess their true significance.

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[frequency of next (right) word to significant]

(1)67 differences	(15)5 correlations	(29)3 influence	(44)2 dose-dependent
(2)40 increase	(16)5 effects	(30)3 negative	(45)2 elevation
(3)36 difference	(17)5 for	(31)3 number	(46)2 evidence
(4)28 decrease	(18)5 increases	(32)3 roles	(47)2 factors
(5)12 reduction	(19)5 risk	(33)2 (P	(48)2 group
(6)11 predictors	(20)4 effect	(35)2 alterations	(49)2 inhibition
(7)10 association	(21)4 in	(36)2 and	(50)2 interaction
(8)9 improvement	(22)4 reductions	(37)2 at	(51)2 morbidity
(9)8 null	(23)4 relationship	(38)2 between-group	(52)2 positive
(10)7 changes	(24)3 (p	(39)2 blood	(53)2 prediction
(11)7 predictor	(25)3 alteration	(40)2 challenge	(54)2 proportion
(12)7 role	(26)3 as	(41)2 contribution	(55)2 source
(13)6 correlation	(27)3 higher	(42)2 cytotoxic	(56)2 time
(14)5 associations	(28)3 improvements	(43)2 decreases

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--- WordNet output for significant --- =>意義深い, 重大な, 意味のある, 意味ありげな, 重要な Overview of adj significant The adj significant has 4 senses (first 4 from tagged texts) 1. (18) significant, important -- (important in effect or meaning; "a significant change in tax laws"; "a significant change in the Constitution"; "a significant contribution"; "significant details"; "statistically significant") 2. (9) significant, substantial -- (fairly large; "won by a substantial margin") 3. (3) significant -- (too closely correlated to be attributed to chance and therefore indicating a systematic relation; "the interaction effect is significant at the .01 level"; "no significant difference was found") 4. (2) meaning, pregnant, significant -- (rich in significance or implication; "a meaning look") --- WordNet end ---