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return kwic search for significant out of >500 occurrences
583352 occurrences (No.14 in the rank) during 5 years in the PubMed. [no cache] 500 found

255) Significant correlations were obtained between adversity scores and change cortisol secretion after TSST in HB patients, but not in healthy participants.

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PMID:24027046 DOI:10.1002/smi.2525

2015 Stress and health : journal of the International Society for the Investigation of Stress

* Physiological and subjective responses after psychosocial stress in Chinese hepatitis B patients.

- Compared with healthy participants, Chinese patients with hepatitis B (HB) experience more psychosocial stress. The present study provided the first examination of physiological and subjective responses to stress in Chinese HB patients. A standard psychosocial stressor, the Trier Social Stress Test (TSST), was administered to 26 Chinese HB patients and 24 healthy control participants. Cortisol concentrations were measured in blood samples collected before and after the stressor. Self-reported emotional responses and cardiovascular measures were examined before and after the TSST. Depression and anxiety were assessed using Hospital Anxiety and Depression Scale. Chinese HB patients exhibited higher cortisol response to the stressor than healthy control participants. Compared with healthy participants, Chinese HB patients showed higher levels of anxiety, depression and nervousness, and lower levels of calmness after the TSST. HB patients reported more negative life events in the previous 6 months and obtained higher adversity scores, as compared with control participants. Significant correlations were obtained between adversity scores and change cortisol secretion after TSST in HB patients, but not in healthy participants. This study firstly demonstrates that physiological and subjective responses to psychosocial stress among Chinese HB patients were different from that in healthy control participants.

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(1)67 differences	(15)5 correlations	(29)3 influence	(44)2 dose-dependent
(2)40 increase	(16)5 effects	(30)3 negative	(45)2 elevation
(3)36 difference	(17)5 for	(31)3 number	(46)2 evidence
(4)28 decrease	(18)5 increases	(32)3 roles	(47)2 factors
(5)12 reduction	(19)5 risk	(33)2 (P	(48)2 group
(6)11 predictors	(20)4 effect	(35)2 alterations	(49)2 inhibition
(7)10 association	(21)4 in	(36)2 and	(50)2 interaction
(8)9 improvement	(22)4 reductions	(37)2 at	(51)2 morbidity
(9)8 null	(23)4 relationship	(38)2 between-group	(52)2 positive
(10)7 changes	(24)3 (p	(39)2 blood	(53)2 prediction
(11)7 predictor	(25)3 alteration	(40)2 challenge	(54)2 proportion
(12)7 role	(26)3 as	(41)2 contribution	(55)2 source
(13)6 correlation	(27)3 higher	(42)2 cytotoxic	(56)2 time
(14)5 associations	(28)3 improvements	(43)2 decreases

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--- WordNet output for significant --- =>意義深い, 重大な, 意味のある, 意味ありげな, 重要な Overview of adj significant The adj significant has 4 senses (first 4 from tagged texts) 1. (18) significant, important -- (important in effect or meaning; "a significant change in tax laws"; "a significant change in the Constitution"; "a significant contribution"; "significant details"; "statistically significant") 2. (9) significant, substantial -- (fairly large; "won by a substantial margin") 3. (3) significant -- (too closely correlated to be attributed to chance and therefore indicating a systematic relation; "the interaction effect is significant at the .01 level"; "no significant difference was found") 4. (2) meaning, pregnant, significant -- (rich in significance or implication; "a meaning look") --- WordNet end ---