ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -
return
kwic search for significant out of >500 occurrences
583352 occurrences (No.14 in the rank) during 5 years in the PubMed. [no cache]
500 found
242) While this is likely true at higher radiation doses (>1 Gy), at low doses (<100 mGy) non-targeted effects associated with radiation exposure might play a significant role.
* Non-targeted effects induced by ionizing radiation: mechanisms and potential impact on radiation induced health effects.
- Not-targeted effects represent a paradigm shift from the "DNA centric" view that ionizing radiation only elicits biological effects and subsequent health consequences as a result of an energy deposition event in the cell nucleus. While this is likely true at higher radiation doses (>1 Gy), at low doses (<100 mGy) non-targeted effects associated with radiation exposure might play a significant role. Here definitions of non-targeted effects are presented, the potential mechanisms for the communication of signals and signaling networks from irradiated cells/tissues are proposed, and the various effects of this intra- and intercellular signaling are described. We conclude with speculation on how these observations might lead to and impact long-term human health outcomes.
=>意義深い, 重大な, 意味のある, 意味ありげな, 重要な
Overview of adj significant
The adj significant has 4 senses (first 4 from tagged texts)
1. (18) significant, important -- (important in effect or meaning; "a significant change in tax
laws"; "a significant change in the Constitution"; "a significant contribution"; "significant
details"; "statistically significant")
2. (9) significant, substantial -- (fairly large; "won by a substantial margin")
3. (3) significant -- (too closely correlated to be attributed to chance and therefore indicating a
systematic relation; "the interaction effect is significant at the .01 level"; "no significant
difference was found")
4. (2) meaning, pregnant, significant -- (rich in significance or implication; "a meaning look")
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