ELIZA

return kwic search for showed out of >500 occurrences
663834 occurrences (No.9 in the rank) during 5 years in the PubMed. [no cache] 500 found

271) Results showed the engineered microenvironment influenced breast cancer cell proliferation, differentiation and migration through multi-cellular interactions and changes in microenvironmental stiffness and that stromal cells such as adipocytes play a critical role in the breast cancer process.

--- ABSTRACT ---

PMID:23307775 DOI:10.1002/term.1660

2015 Journal of tissue engineering and regenerative medicine

* Designing a tunable 3D heterocellular breast cancer tissue test system.

- It is increasingly recognized that the tissue microenvironment is crucial in cell signaling and regulation of normal and malignant cell function. Components and properties of the microenvironment such as extracellular matrix, adhesion integrins, tissue architectures and tissue modulus regulate growth, differentiation and apoptosis of cells. These properties control cell fate through complex signals that are influenced either by interactions between neighbouring cells or by stimulated cell surface receptors. In this study, we established an in vitro engineered microenvironment: i.e., a tissue test system that combined heterocellular tumour spheroids, polymeric microcarriers and adipocytes, an abundant stromal cell type in breast tissue, to investigate the behaviour of breast cancer cells in response to different environmental stimuli in a more relevant 3D microenvironment. Results showed the engineered microenvironment influenced breast cancer cell proliferation, differentiation and migration through multi-cellular interactions and changes in microenvironmental stiffness and that stromal cells such as adipocytes play a critical role in the breast cancer process.

--- ABSTRACT END ---

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[frequency of next (right) word to showed]

(1)155 that	(8)6 high	(15)3 reduced	(22)2 dense
(2)87 a	(9)5 significantly	(16)3 very	(23)2 distinct
(3)25 significant	(10)4 similar	(17)2 40%	(24)2 enhanced
(4)16 the	(11)4 statistically	(18)2 cardiomegaly	(25)2 good
(5)15 no	(12)3 decreased	(19)2 close	(26)2 greater
(6)13 higher	(13)3 increased	(20)2 complete	(27)2 moderate
(7)11 an	(14)3 prominent	(21)2 considerable	(28)2 more

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--- WordNet output for showed --- Overview of verb show The verb show has 12 senses (first 11 from tagged texts) 1. (136) show, demo, exhibit, present, demonstrate -- (give an exhibition of to an interested audience; "She shows her dogs frequently"; "We will demo the new software in Washington") 2. (63) prove, demonstrate, establish, show, shew -- (establish the validity of something, as by an example, explanation or experiment; "The experiment demonstrated the instability of the compound"; "The mathematician showed the validity of the conjecture") 3. (57) testify, bear witness, prove, evidence, show -- (provide evidence for; "The blood test showed that he was the father"; "Her behavior testified to her incompetence") 4. (43) show -- (make visible or noticeable; "She showed her talent for cooking"; "Show me your etchings, please") 5. (32) picture, depict, render, show -- (show in, or as in, a picture; "This scene depicts country life"; "the face of the child is rendered with much tenderness in this painting") 6. (24) express, show, evince -- (give expression to; "She showed her disappointment") 7. (24) indicate, point, designate, show -- (indicate a place, direction, person, or thing; either spatially or figuratively; "I showed the customer the glove section"; "He pointed to the empty parking space"; "he indicated his opponents") 8. (11) show, show up -- (be or become visible or noticeable; "His good upbringing really shows"; "The dirty side will show") 9. (7) read, register, show, record -- (indicate a certain reading; of gauges and instruments; "The thermometer showed thirteen degrees below zero"; "The gauge read `empty'") 10. (6) show -- (give evidence of, as of records; "The diary shows his distress that evening") 11. (2) usher, show -- (take (someone) to their seats, as in theaters or auditoriums; "The usher showed us to our seats") 12. show -- (finish third or better in a horse or dog race; "he bet $2 on number six to show") --- WordNet end ---