ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for response out of >500 occurrences
343831 occurrences (No.54 in the rank) during 5 years in the PubMed. [no cache] 500 found
18) In agreement with the results of in vitro studies, ISH against human Alu sequences showed that host mouse MSCs migrated in large numbers into the transplantation site in response to O-hMSCs.
--- ABSTRACT ---
PMID:23038663 DOI:10.1002/term.1619
2015 Journal of tissue engineering and regenerative medicine
* Implantation of osteogenic differentiated donor mesenchymal stem cells causes recruitment of host cells.
- The interaction between host and donor cells is believed to play an important role in osteogenesis. However, it is still unclear how donor osteogenic cells behave and interact with host cells in vivo. The purpose of this study was to track the interactions between transplanted osteogenic cells and host cells during osteogenesis. In vitro migration assay was carried out to investigate the ability of osteogenic differentiated human mesenchymal stem cells (O-hMSCs) to recruit MSCs. At the in vivo level, O-hMSCs were implanted subcutaneously or into skull defects in severe combined immunodeficient (SCID) mice. New bone formation was observed by micro-CT and histological procedures. In situ hybridization (ISH) against human Alu sequences was performed to distinguish donor osteogenic cells from host cells. In vitro migration assay revealed an increased migration potential of MSCs by co-culturing with O-hMSCs. In agreement with the results of in vitro studies, ISH against human Alu sequences showed that host mouse MSCs migrated in large numbers into the transplantation site in response to O-hMSCs. Interestingly, host cells recruited by O-hMSCs were the major cell populations in newly formed bone tissues, indicating that O-hMSCs can trigger and initiate osteogenesis when transplanted in orthotopic sites. The observations from this study demonstrated that in vitro induced O-hMSCs were able to attract host MSCs in vivo and were involved in osteogenesis together with host cells, which may be of importance for bone tissue-engineering applications.
--- ABSTRACT END ---
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(1)146 to (14)4 proteins (27)3 time (40)2 following
(2)32 *null* (15)4 rates (28)3 times (41)2 from
(3)31 and (16)4 that (29)3 which (42)2 including
(4)22 of (17)4 the (30)2 (ABR) (43)2 latency
(5)21 rate (18)3 at (31)2 (DDR) (44)2 mediated
(6)14 was (19)3 during (32)2 (UPR) (45)2 or
(7)13 in (20)3 elements (33)2 after (46)2 rate)
(8)8 selection (21)3 models (34)2 are (47)2 rates,
(9)7 surface (22)3 options (35)2 boundaries (48)2 such
(10)6 data (23)3 properties (36)2 delays (49)2 theory
(11)6 is (24)3 strategies (37)2 effects (50)2 validity
(12)4 for (25)3 style (38)2 element (51)2 were
(13)4 patterns (26)3 suppression (39)2 evaluation

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--- WordNet output for response --- =>反応, 応答, 返答, 返報, 反響, 答唱句 Overview of noun response The noun response has 7 senses (first 5 from tagged texts) 1. (11) response -- (a result; "this situation developed in response to events in Africa") 2. (11) reaction, response -- (a bodily process occurring due to the effect of some antecedent stimulus or agent; "a bad reaction to the medicine"; "his responses have slowed with age") 3. (6) answer, reply, response -- (a statement (either spoken or written) that is made to reply to a question or request or criticism or accusation; "I waited several days for his answer"; "he wrote replies to several of his critics") 4. (4) reception, response -- (the manner in which something is greeted; "she did not expect the cold reception she received from her superiors") 5. (1) response -- (a phrase recited or sung by the congregation following a versicle by the priest or minister) 6. reply, response -- (the speech act of continuing a conversational exchange; "he growled his reply") 7. response -- (the manner in which an electrical or mechanical device responds to an input signal or a range of input signals) --- WordNet end ---