ELIZA

return kwic search for research out of >500 occurrences
280501 occurrences (No.89 in the rank) during 5 years in the PubMed. [no cache] 500 found

246) Ongoing research suggests a potential important added role for natriuretic peptides in heart failure.

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PMID:24251462 DOI:10.1111/jan.12297

2015 Current cardiology reviews

* Evolution of biomarker guided therapy for heart failure: current concepts and trial evidence.

- Optimizing management of patients with heart failure remains quite challenging despite many significant advances in drug and device therapy for this syndrome. Although a large body of evidence from robust clinical trials supports multiple therapies, utilization of these well-established treatments remains inconsistent and outcomes suboptimal in "real-world" patients with heart failure. Disease management programs may be effective, but are difficult to implement due to cost and logistical issues. Another approach to optimizing therapy is to utilize biomarkers to guide therapeutic choices. Natriuretic peptides provide additional information of significant clinical value in the diagnosis and estimation of risk inpatients with heart failure. Ongoing research suggests a potential important added role for natriuretic peptides in heart failure. Guiding therapy based on serial changes in these biomarkers may be an effective strategy to optimize treatment and achieve better outcomes in this syndrome. Initial, innovative, proof-of-concept studies have provided encouraging results and important insights into key aspects of this strategy, but well designed, large-scale, multicenter, randomized, outcome trials are needed to definitively establish this novel approach to management. Given the immense and growing public health burden of heart failure, identification of cost-effective ways to decrease the morbidity and mortality due to this syndrome is critical.

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[frequency of next (right) word to research]

(1)42 null	(14)7 that	(27)3 as	(40)2 from
(2)40 on	(15)6 by	(28)3 directions	(41)2 involving
(3)36 is	(16)6 to	(29)3 evidence	(42)2 participants,
(4)27 and	(17)5 projects	(30)3 have	(43)2 progress
(5)25 has	(18)4 culture	(31)3 method	(44)2 sponsored
(6)14 in	(19)4 design	(32)3 results	(45)2 the
(7)12 was	(20)4 findings	(33)3 shows	(46)2 topic
(8)11 are	(21)4 needs	(34)3 study	(47)2 towards
(9)11 should	(22)4 project	(35)3 will	(48)2 trends
(10)9 into	(23)4 questions	(36)2 efforts	(49)2 using
(11)9 with	(24)4 regarding	(37)2 examined	(50)2 we
(12)8 studies	(25)3 &	(38)2 focus	(51)2 work
(13)8 suggests	(26)3 aimed	(39)2 for

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--- WordNet output for research --- =>調査する, 研究(する), 探求, 調査, 捜索, 研究する Overview of noun research The noun research has 2 senses (first 2 from tagged texts) 1. (46) research -- (systematic investigation to establish facts) 2. (6) inquiry, enquiry, research -- (a search for knowledge; "their pottery deserves more research than it has received") Overview of verb research The verb research has 2 senses (first 1 from tagged texts) 1. (1) research -- (attempt to find out in a systematically and scientific manner; "The student researched the history of that word") 2. research, search, explore -- (inquire into; "the students had to research the history of the Second World War for their history project"; "He searched for information on his relatives on the web"; "Scientists are exploring the nature of consciousness") --- WordNet end ---