* The effect of adding ezetimibe to rosuvastatin on renal function in patients undergoing elective vascular surgery.
- We compared the effects of lipid lowering with rosuvastatin (RSV) monotherapy versus intensified treatment by combining RSV with ezetimibe (EZT) on kidney function in patients undergoing vascular surgery. Patients were randomly assigned to either 10 mg/d RSV (n = 136) or RSV 10 mg/d plus EZT 10 mg/d (RSV/EZT, n = 126). At 12 months, a similar decrease in estimated glomerular filtration rate (eGFR) was noted. Patients who achieved a low-density lipoprotein cholesterol (LDL-C) of <100 mg/dL had less eGFR decrease than those patients having an LDL-C limit of more than 100 mg/dL. There were no significant changes in the urinary total protein to creatinine ratio in either group. Significant microalbuminuria was evident in both the groups. Patients undergoing vascular surgery show deterioration in their renal function during the first year, despite statin therapy. Intensified lipid-lowering therapy by adding EZT does not appear to have any renoprotective effect.
=>価格を評定する, 割合, 率, 歩合, 料金, 値段, 相場, 速度, 度合, 人を〜を思う, みなす, 価値がある,
人を〜とみなす, 科金, 評価する
Overview of noun rate
The noun rate has 4 senses (first 3 from tagged texts)
1. (68) rate -- (a magnitude or frequency relative to a time unit; "they traveled at a rate of 55
miles per hour"; "the rate of change was faster than expected")
2. (39) rate, charge per unit -- (amount of a charge or payment relative to some basis; "a 10-minute
phone call at that rate would cost $5")
3. (1) pace, rate -- (the relative speed of progress or change; "he lived at a fast pace"; "he works
at a great rate"; "the pace of events accelerated")
4. rate -- (a quantity or amount or measure considered as a proportion of another quantity or amount
or measure; "the literacy rate"; "the retention rate"; "the dropout rate")
Overview of verb rate
The verb rate has 3 senses (first 3 from tagged texts)
1. (9) rate, rank, range, order, grade, place -- (assign a rank or rating to; "how would you rank
these students?"; "The restaurant is rated highly in the food guide")
2. (2) rate -- (be worthy of or have a certain rating; "This bond rates highly")
3. (1) rate, value -- (estimate the value of; "How would you rate his chances to become President?";
"Gold was rated highly among the Romans")
--- WordNet end ---