ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for protein out of >500 occurrences
536761 occurrences (No.22 in the rank) during 5 years in the PubMed. [cache]
207) Estradiol in vivo in obese rats resulted in a significant increase in protein kinase B (Akt) activation (P < .05) and decrease in heart mass (P < .05), ratio of the heart mass/body mass (P < .05), transverse diameters of cardiomyocytes (P < .001), concentration of serum high-sensitivity C-reactive protein (P < .001), and total cholesterol (P < .01) compared with obese nontreated rats.
--- ABSTRACT ---
PMID:24327768 DOI:10.1177/0003319713514477
2015 Angiology
* Estradiol in vivo induces changes in cardiomyocytes size in obese rats.
- We studied the in vivo effects of estradiol on size and biochemical parameters of cardiomyocytes in pathophysiological conditions such as obesity and insulin resistance. Male Wistar rats were normally fed (controls, n = 7) or fed with high-fat diet (obese, n = 14). Half of the obese rats (obese + estradiol, n = 7) were treated with a single dose of estradiol (40 μg/kg, intraperitoneally) and 24 hours after treatment all the rats were killed. Estradiol in vivo in obese rats resulted in a significant increase in protein kinase B (Akt) activation (P < .05) and decrease in heart mass (P < .05), ratio of the heart mass/body mass (P < .05), transverse diameters of cardiomyocytes (P < .001), concentration of serum high-sensitivity C-reactive protein (P < .001), and total cholesterol (P < .01) compared with obese nontreated rats. Our results suggest that estradiol in obese/IR rats affects the size of cardiomyocytes and its actions lead in vivo to a reduction in obesity-induced cardiac hypertrophy, via Akt.
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[frequency of next (right) word to protein]
(1)76 genes, (11)8 was (21)3 has (31)2 for
(2)45 genes (12)7 level (22)3 is (32)2 initiation
(3)24 and (13)6 carbonyl (23)3 of (33)2 level,
(4)23 levels (14)6 coding (24)3 oxidation, (34)2 production
(5)18 expression (15)5 C (25)3 stability (35)2 sequences
(6)12 *null* (16)5 gene (26)3 thiol (36)2 solutions
(7)12 kinase (17)5 isolate (27)2 acid (37)2 structures
(8)9 1 (18)5 kinases (28)2 content (38)2 that
(9)9 in (19)4 levels, (29)2 contents
(10)8 2 (20)3 expression, (30)2 families

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--- WordNet output for protein --- =>タンパク質, 蛋白質, たん白質 Overview of noun protein The noun protein has 1 sense (first 1 from tagged texts) 1. (23) protein -- (any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein") --- WordNet end ---