ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for present out of >500 occurrences
505151 occurrences (No.26 in the rank) during 5 years in the PubMed. [no cache] 500 found
218) In the present study, five developmentally important genes (HPRT1, Cx43, Sox2, Mest and IGF2R) were analysed at different stages in parthenotes (haploid and diploid) and compared with similar stages in in vitro fertilized (IVF) embryos.
--- ABSTRACT ---
PMID:24229648 DOI:10.1017/S096719941300049X
2015 Zygote (Cambridge, England)
* Comparative expression analysis of embryonic development-related genes at different stages of parthenogenetic and in vitro fertilized embryos in caprine.
- Aberrant gene expression occurs in parthenogenetic embryos due to abnormal epigenetic modifications in the genome that probably diminish viability and enhance developmental abnormalities in these embryos. In the present study, five developmentally important genes (HPRT1, Cx43, Sox2, Mest and IGF2R) were analysed at different stages in parthenotes (haploid and diploid) and compared with similar stages in in vitro fertilized (IVF) embryos. The results indicated that in haploid parthenotes expression of HPRT1 was upregulated (P < 0.05) only at the 2-4-cell stage whereas Cx43 expression was significantly (P < 0.05) downregulated in all stages as compared with the control. However, expression of this gene was upregulated (P < 0.05) in 2-4-cell and morula stages of diploid parthenotes. Expression of Sox2 was significantly (P < 0.05) downregulated in morula stage haploid parthenotes, whereas it was upregulated (P < 0.05) in 8-16-cell stage diploid embryos. The expression of Mest was upregulated (P < 0.05) at the 2-4-cell stage of both haploid and diploid parthenotes, whereas it was downregulated in 8-16-cell stage diploid embryos as compared with control. IGF2R expression was upregulated (P < 0.05) only in morula stage haploid and diploid parthenote as compared with control. These results indicate that parthenogenetic embryos showed aberrant gene expression of developmentally important genes such as HPRT1, Cx43, Sox2, Mest and IGF2R in comparison with IVF embryos, this finding may be one of the major reasons for the poor developmental competence of parthenogenetic embryos.
--- ABSTRACT END ---
[
right
kwic]
[frequency of next (right) word to present]
(1)151 study (10)8 review (19)3 findings (28)2 only
(2)60 a (11)7 investigation (20)3 on (29)2 paper,
(3)37 study, (12)6 an (21)3 our (30)2 report,
(4)36 in (13)6 case (22)3 research (31)2 studies
(5)21 the (14)5 article (23)2 as (32)2 this
(6)10 results (15)5 data (24)2 between (33)2 to
(7)9 *null* (16)4 and (25)2 case, (34)2 work
(8)9 with (17)4 here (26)2 either
(9)8 at (18)4 two (27)2 more

add keyword

--- WordNet output for present --- =>出席している, そこにある, 現在の, 今の, 当面の, いあわせている, 考慮している, 現在, を人に贈る, 進呈する, を与える, を渡す, を紹介する, を公開する, を見せる, 示す, 贈り物, 【文法】現在時制の, プレゼント, 贈る, ある, 現在形の Overview of noun present The noun present has 3 senses (first 2 from tagged texts) 1. (17) present, nowadays -- (the period of time that is happening now; any continuous stretch of time including the moment of speech; "that is enough for the present"; "he lives in the present with no thought of tomorrow") 2. (4) present -- (something presented as a gift; "his tie was a present from his wife") 3. present, present tense -- (a verb tense that expresses actions or states at the time of speaking) Overview of verb present The verb present has 13 senses (first 10 from tagged texts) 1. (40) show, demo, exhibit, present, demonstrate -- (give an exhibition of to an interested audience; "She shows her dogs frequently"; "We will demo the new software in Washington") 2. (28) present, represent, lay out -- (bring forward and present to the mind; "We presented the arguments to him"; "We cannot represent this knowledge to our formal reason") 3. (14) stage, present, represent -- (perform (a play), especially on a stage; "we are going to stage `Othello'") 4. (13) present, submit -- (hand over formally) 5. (7) present, pose -- (introduce; "This poses an interesting question") 6. (3) award, present -- (give, especially as an honor or reward; "bestow honors and prizes at graduation") 7. (3) give, gift, present -- (give as a present; make a gift of; "What will you give her for her birthday?") 8. (3) deliver, present -- (deliver (a speech, oration, or idea); "The commencement speaker presented a forceful speech that impressed the students") 9. (2) introduce, present, acquaint -- (cause to come to know personally; "permit me to acquaint you with my son"; "introduce the new neighbors to the community") 10. (1) portray, present -- (represent abstractly, for example in a painting, drawing, or sculpture; "The father is portrayed as a good-looking man in this painting") 11. confront, face, present -- (present somebody with something, usually to accuse or criticize; "We confronted him with the evidence"; "He was faced with all the evidence and could no longer deny his actions"; "An enormous dilemma faces us") 12. present -- (formally present a debutante, a representative of a country, etc.) 13. salute, present -- (recognize with a gesture prescribed by a military regulation; assume a prescribed position; "When the officers show up, the soldiers have to salute") Overview of adj present The adj present has 2 senses (first 2 from tagged texts) 1. (60) present -- (temporal sense; intermediate between past and future; now existing or happening or in consideration; "the present leader"; "articles for present use"; "the present topic"; "the present system"; "present observations") 2. (39) present -- (being or existing in a specified place; "the murderer is present in this room"; "present at the wedding"; "present at the creation") --- WordNet end ---