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505151 occurrences (No.26 in the rank) during 5 years in the PubMed. [no cache] 500 found

10) Therefore, the present study aimed to use FN immunoreactivity (FN-ir) as a marker for early detection of rheumatic susceptible children with palatine tonsil crypts surface epithelium.

--- ABSTRACT ---

PMID:23315088 DOI:10.1177/0748233712471701

2015 Toxicology and industrial health

* Fibronectin in the palatine tonsil as a susceptibility marker in Egyptian rheumatic families: histological and immunohistochemical studies.

- Rheumatic fever (RF) and rheumatic heart disease (RHD) are the multisystem autoimmune sequel of group A streptococci (GAS) infection of the upper respiratory passages, mainly tonsillopharyngitis. The major receptor on the surface of human palatine tonsil for GAS is fibronectin (FN; adhesin receptor). Early detection of RF susceptibility is considered as an important aim of this study. Therefore, the present study aimed to use FN immunoreactivity (FN-ir) as a marker for early detection of rheumatic susceptible children with palatine tonsil crypts surface epithelium. A total of 30 palatine tonsillar specimens were obtained from children aged from 3 to 15 years. Histological studies showed moderate vascular changes and more than four apparent epithelial disruptions in the crypt epithelium. FN-ir showed a significant increase in FN in the basal layers of surface epithelium, subepithelial connective tissue and interfollicular areas. Tonsils of children in rheumatic families showed significant increase in FN in subepithelial connective tissue areas with more than one apparent crypt epithelial disruption compared to normal children. We can conclude that FN plays a central role in the RF and differentially distributed in the functional compartments of the palatine tonsil in children with RHD, so FN-ir can be used as a marker for rheumatic susceptibility.

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(1)151 study	(10)8 review	(19)3 findings	(28)2 only
(2)60 a	(11)7 investigation	(20)3 on	(29)2 paper,
(3)37 study,	(12)6 an	(21)3 our	(30)2 report,
(4)36 in	(13)6 case	(22)3 research	(31)2 studies
(5)21 the	(14)5 article	(23)2 as	(32)2 this
(6)10 results	(15)5 data	(24)2 between	(33)2 to
(7)9 null	(16)4 and	(25)2 case,	(34)2 work
(8)9 with	(17)4 here	(26)2 either
(9)8 at	(18)4 two	(27)2 more

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--- WordNet output for present --- =>出席している, そこにある, 現在の, 今の, 当面の, いあわせている, 考慮している, 現在, を人に贈る, 進呈する, を与える, を渡す, を紹介する, を公開する, を見せる, 示す, 贈り物, 【文法】現在時制の, プレゼント, 贈る, ある, 現在形の Overview of noun present The noun present has 3 senses (first 2 from tagged texts) 1. (17) present, nowadays -- (the period of time that is happening now; any continuous stretch of time including the moment of speech; "that is enough for the present"; "he lives in the present with no thought of tomorrow") 2. (4) present -- (something presented as a gift; "his tie was a present from his wife") 3. present, present tense -- (a verb tense that expresses actions or states at the time of speaking) Overview of verb present The verb present has 13 senses (first 10 from tagged texts) 1. (40) show, demo, exhibit, present, demonstrate -- (give an exhibition of to an interested audience; "She shows her dogs frequently"; "We will demo the new software in Washington") 2. (28) present, represent, lay out -- (bring forward and present to the mind; "We presented the arguments to him"; "We cannot represent this knowledge to our formal reason") 3. (14) stage, present, represent -- (perform (a play), especially on a stage; "we are going to stage `Othello'") 4. (13) present, submit -- (hand over formally) 5. (7) present, pose -- (introduce; "This poses an interesting question") 6. (3) award, present -- (give, especially as an honor or reward; "bestow honors and prizes at graduation") 7. (3) give, gift, present -- (give as a present; make a gift of; "What will you give her for her birthday?") 8. (3) deliver, present -- (deliver (a speech, oration, or idea); "The commencement speaker presented a forceful speech that impressed the students") 9. (2) introduce, present, acquaint -- (cause to come to know personally; "permit me to acquaint you with my son"; "introduce the new neighbors to the community") 10. (1) portray, present -- (represent abstractly, for example in a painting, drawing, or sculpture; "The father is portrayed as a good-looking man in this painting") 11. confront, face, present -- (present somebody with something, usually to accuse or criticize; "We confronted him with the evidence"; "He was faced with all the evidence and could no longer deny his actions"; "An enormous dilemma faces us") 12. present -- (formally present a debutante, a representative of a country, etc.) 13. salute, present -- (recognize with a gesture prescribed by a military regulation; assume a prescribed position; "When the officers show up, the soldiers have to salute") Overview of adj present The adj present has 2 senses (first 2 from tagged texts) 1. (60) present -- (temporal sense; intermediate between past and future; now existing or happening or in consideration; "the present leader"; "articles for present use"; "the present topic"; "the present system"; "present observations") 2. (39) present -- (being or existing in a specified place; "the murderer is present in this room"; "present at the wedding"; "present at the creation") --- WordNet end ---