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163) Collectively, the reported data support the conclusion that PDS-HNTs nanocomposite fibrous structures hold potential in the development of a bioactive scaffold for regenerative endodontics.
2015 Journal of tissue engineering and regenerative medicine
* A novel three-dimensional scaffold for regenerative endodontics: materials and biological characterizations.
- An electrospun nanocomposite fibrous material holds promise as a scaffold, as well as a drug-delivery device to aid in root maturogenesis and the regeneration of the pulp-dentine complex. A novel three-dimensional (3D) nanocomposite scaffold composed of polydioxanone (PDS II®) and halloysite nanotubes (HNTs) was designed and fabricated by electrospinning. Morphology, structure, mechanical properties and cell compatibility studies were carried out to evaluate the effects of HNTs incorporation (0.5-10 wt% relative to PDS w/w). Overall, a 3D porous network was seen in the different fabricated electrospun scaffolds, regardless of the HNT content. The incorporation of HNTs at 10 wt% led to a significant (p < 0.0001) fibre diameter increase and a reduction in scaffold strength. Moreover, PDS-HNTs scaffolds supported the attachment and proliferation of human-derived pulp fibroblast cells. Quantitative proliferation assay performed with human dental pulp-derived cells as a function of nanotubes concentration indicated that the HNTs exhibit a high level of biocompatibility, rendering them good candidates for the potential encapsulation of distinct bioactive molecules. Collectively, the reported data support the conclusion that PDS-HNTs nanocomposite fibrous structures hold potential in the development of a bioactive scaffold for regenerative endodontics.
=>可能性のある, 可能な, 潜在力のある, 位置の, 電位の, 潜在的な, ポテンシャル, 可能性, 電位
Overview of noun potential
The noun potential has 2 senses (first 1 from tagged texts)
1. (10) potential, potentiality, potency -- (the inherent capacity for coming into being)
2. electric potential, potential, potential difference, potential drop, voltage -- (the difference
in electrical charge between two points in a circuit expressed in volts)
Overview of adj potential
The adj potential has 2 senses (first 2 from tagged texts)
1. (7) potential, possible -- (existing in possibility; "a potential problem"; "possible uses of
nuclear power")
2. (6) likely, potential -- (expected to become or be; in prospect; "potential clients")
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