ELIZA

return kwic search for patients with out of >500 occurrences
404916 occurrences (No.41 in the rank) during 5 years in the PubMed. [cache]

252) To determine whether in vitro behaviour differs between primary osteosarcoma cell lines generated from patients with normal or increased serum ALP, assays were performed to evaluate proliferation, migration, invasion and chemosensitivity.

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PMID:23489774 DOI:10.1111/vco.12031

2015 Veterinary and comparative oncology

* Canine osteosarcoma cell lines from patients with differing serum alkaline phosphatase concentrations display no behavioural differences in vitro.

- Osteosarcoma is an aggressive malignancy and represents the most frequent primary bone malignancy of dogs and humans. Prognostic factors reported for osteosarcoma include tumour size, presence of metastatic disease and serum alkaline phosphatase (ALP) concentration at the time of diagnosis. To date, there have been no studies to determine whether the behaviour of osteosarcoma cells differ based on serum ALP concentration. Here, we report on the generation of six canine osteosarcoma cell lines from osteosarcoma-bearing dogs with differences in serum ALP concentration. To determine whether in vitro behaviour differs between primary osteosarcoma cell lines generated from patients with normal or increased serum ALP, assays were performed to evaluate proliferation, migration, invasion and chemosensitivity. There were no significant differences in cell proliferation, migration, invasion or chemosensitivity between cell lines associated with normal or increased serum ALP concentration.

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(1)23 chronic	(21)3 AD	(41)2 CAD	(61)2 critical
(2)13 a	(22)3 AgP	(42)2 CKD	(62)2 diabetes,
(3)10 diabetes	(23)3 CTD	(43)2 CVD	(63)2 early
(4)9 acute	(24)3 an	(44)2 DIC	(64)2 equal
(5)8 severe	(25)3 cardiovascular	(45)2 LGV	(65)2 hard-to-heal
(6)6 cancer	(26)3 comorbid	(46)2 MFS	(66)2 higher
(7)6 congenital	(27)3 end-stage	(47)2 NE	(67)2 ischemic
(8)5 RA	(28)3 fibromyalgia	(48)2 NSTE-ACS	(68)2 lesions
(9)5 and	(29)3 heart	(49)2 SS	(69)2 limited
(10)5 hypertension	(30)3 known	(50)2 SSc	(70)2 moderate
(11)5 type	(31)3 nonvalvular	(51)2 ST-segment	(71)2 no
(12)4 STEMI	(32)3 osteoarthritis	(52)2 VLUs	(72)2 normal
(13)4 advanced	(33)3 ovarian	(53)2 VTE	(73)2 pressure
(14)4 breast	(34)3 poor	(54)2 angina	(74)2 prior
(15)4 dementia	(35)3 schizophrenia	(55)2 antiheparin/PF4	(75)2 refractory
(16)4 low	(36)3 sickle	(56)2 asthma	(76)2 sarcoidosis
(17)4 sepsis	(37)3 symptomatic	(57)2 atrial	(77)2 somatoform
(18)4 stable	(38)3 the	(58)2 central	(78)2 stroke
(19)4 this	(39)2 AHA	(59)2 clinical	(79)2 sudden
(20)4 venous	(40)2 BD	(60)2 coronary

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--- WordNet output for patients --- Overview of noun patient The noun patient has 2 senses (first 1 from tagged texts) 1. (73) patient -- (a person who requires medical care; "the number of emergency patients has grown rapidly") 2. affected role, patient role, patient -- (the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause) --- WordNet end ---