ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for lower out of >500 occurrences
288686 occurrences (No.85 in the rank) during 5 years in the PubMed. [no cache] 500 found
333) The DEP-sample with the highest PAH and lowest metal content was more potent with respect to cytotoxicity and expression and release of proinflammatory mediators, CYP1A1 and HO-1 expression and MAPK activation, than the DEP-sample with lower PAH and higher metal content.
--- ABSTRACT ---
PMID:23900936 DOI:10.1002/tox.21884
2015 Environmental toxicology
* Differential proinflammatory responses induced by diesel exhaust particles with contrasting PAH and metal content.
- Exposure to diesel engine exhaust particles (DEPs), representing a complex and variable mixture of components, has been linked with cellular production and release of several types of mediators related to pulmonary inflammation. A key challenge is to identify the specific components, which may be responsible for these effects. The aim of this study was to compare the proinflammatory potential of two DEP-samples with contrasting contents of polycyclic aromatic hydrocarbons (PAHs) and metals. The DEP-samples were compared with respect to their ability to induce cytotoxicity, expression and release of proinflammatory mediators (IL-6, IL-8), activation of mitogen-activated protein kinases (MAPKs) and expression of CYP1A1 and heme oxygenase-1 (HO-1) in human bronchial epithelial (BEAS-2B) cells. In addition, dithiothreitol and ascorbic acid assays were performed in order to examine the oxidative potential of the PM samples. The DEP-sample with the highest PAH and lowest metal content was more potent with respect to cytotoxicity and expression and release of proinflammatory mediators, CYP1A1 and HO-1 expression and MAPK activation, than the DEP-sample with lower PAH and higher metal content. The DEP-sample with the highest PAH and lowest metal content also possessed a greater oxidative potential. The present results indicate that the content of organic components may be determinant for the proinflammatory effects of DEP. The findings underscore the importance of considering the chemical composition of particulate matter-emissions, when evaluating the potential health impact and implementation of air pollution regulations.
--- ABSTRACT END ---
[
right
kwic]
[frequency of next (right) word to lower]
(1)38 than (19)4 incidence (37)3 socioeconomic (55)2 expression
(2)35 in (20)4 leg (38)3 stresses (56)2 eyelid
(3)19 levels (21)4 spine (39)3 values (57)2 eyelids
(4)12 extremity (22)4 total (40)2 Condom (58)2 frequencies
(5)11 risk (23)3 (P (41)2 EI (59)2 frequency
(6)7 compared (24)3 *null* (42)2 IQ (60)2 likelihood
(7)7 level (25)3 ASM/wt (43)2 abdominal (61)2 limit
(8)7 limb (26)3 education (44)2 among (62)2 microleakage
(9)5 at (27)3 educational (45)2 back (63)2 perceived
(10)5 for (28)3 extremities, (46)2 birthweight (64)2 percentage
(11)5 limbs (29)3 heart (47)2 bounds (65)2 quality
(12)5 the (30)3 initial (48)2 by (66)2 rate
(13)4 and (31)3 legs (49)2 complication (67)2 resilience
(14)4 body (32)3 mean (50)2 concentration (68)2 serum
(15)4 cervical (33)3 odds (51)2 concentrations (69)2 shear
(16)4 dose (34)3 prevalence (52)2 demineralization
(17)4 doses (35)3 probability (53)2 esophageal
(18)4 extremities (36)3 sexual (54)2 estimated

add keyword

--- WordNet output for lower --- =>1.低くする/なる, 下げる/下がる, 卑しめる, 2.しかめっ面, 3.lowの比較級 Overview of noun lower The noun lower has 1 sense (no senses from tagged texts) 1. lower berth, lower -- (the lower of two berths) Overview of verb lower The verb lower has 5 senses (first 3 from tagged texts) 1. (15) lower, take down, let down, get down, bring down -- (move something or somebody to a lower position; "take down the vase from the shelf") 2. (6) lower, lour -- (set lower; "lower a rating"; "lower expectations") 3. (1) turn down, lower, lour -- (make lower or quieter; "turn down the volume of a radio") 4. lower, depress -- (cause to drop or sink; "The lack of rain had depressed the water level in the reservoir") 5. frown, glower, lour, lower -- (look angry or sullen, wrinkle one's forehead, as if to signal disapproval) Overview of adj low The adj low has 10 senses (first 6 from tagged texts) 1. (55) low -- (less than normal in degree or intensity or amount; "low prices"; "the reservoir is low") 2. (23) low -- (literal meanings; being at or having a relatively small elevation or upward extension; "low ceilings"; "low clouds"; "low hills"; "the sun is low"; "low furniture"; "a low bow") 3. (11) low, low-toned -- (very low in volume; "a low murmur"; "the low-toned murmur of the surf") 4. (6) low -- (unrefined in character; "low comedy") 5. (4) low, low-pitched -- (used of sounds and voices; low in pitch or frequency) 6. (3) abject, low, low-down, miserable, scummy, scurvy -- (of the most contemptible kind; "abject cowardice"; "a low stunt to pull"; "a low-down sneak"; "his miserable treatment of his family"; "You miserable skunk!"; "a scummy rabble"; "a scurvy trick") 7. humble, low, lowly, modest, small -- (low or inferior in station or quality; "a humble cottage"; "a lowly parish priest"; "a modest man of the people"; "small beginnings") 8. depleted, low -- (no longer sufficient; "supplies are low"; "our funds are depleted") 9. broken, crushed, humbled, humiliated, low -- (subdued or brought low in condition or status; "brought low"; "a broken man"; "his broken spirit") 10. gloomy, grim, blue, depressed, dispirited, down, downcast, downhearted, down in the mouth, low, low-spirited -- (filled with melancholy and despondency ; "gloomy at the thought of what he had to face"; "gloomy predictions"; "a gloomy silence"; "took a grim view of the economy"; "the darkening mood"; "lonely and blue in a strange city"; "depressed by the loss of his job"; "a dispirited and resigned expression on her face"; "downcast after his defeat"; "feeling discouraged and downhearted") --- WordNet end ---