ELIZA

return kwic search for low out of >500 occurrences
318584 occurrences (No.68 in the rank) during 5 years in the PubMed. [no cache] 500 found

113) Twenty-four patients with acute bleeding episodes were treated with prothrombin complex concentrate (PCC) at a relative low dose of 30 to -50 U/kg/d and achieved good outcomes without any adverse reaction.

--- ABSTRACT ---

PMID:23677912 DOI:10.1177/1076029613488937

2015 Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis

* Acquired hemophilia a: retrospective analysis of 49 cases from a single Chinese hemophilia center.

- Acquired hemophilia A (AHA) is a rare bleeding disorder caused by the autoantibody directed against factor VIII in patients without previous history of a bleeding disorder. We retrospectively analyzed the characteristics and outcomes of 49 patients with AHA diagnosed in our center from February 1994 to October 2012. Twenty-four patients with acute bleeding episodes were treated with prothrombin complex concentrate (PCC) at a relative low dose of 30 to -50 U/kg/d and achieved good outcomes without any adverse reaction. Corticosteroids alone or in combination with cyclophosphamide were used as the first-line therapy to eradicate the inhibitors. In 39 evaluable patients, 35 (89.7%) achieved complete remission (CR). This study demonstrates that when bypassing agents such as recombinant activated factor VII and activated PCCs are not affordable or available, low dose PCC is effective and safe to control acute bleeding in patients with AHA. First-line therapy achieved good outcomes with a CR rate of 89.7%.

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(1)21 and	(18)4 or	(35)2 Chilean	(52)2 energy
(2)19 laser	(19)4 socioeconomic	(36)2 HLB	(53)2 families
(3)11 doses	(20)3 Er:YAG	(37)2 OAs	(54)2 genetic
(4)11 levels	(21)3 O2	(38)2 acculturation	(55)2 group
(5)10 null	(22)3 PFR	(39)2 activities	(56)2 maternal
(6)10 cost	(23)3 PbB	(40)2 activity	(57)2 method
(7)10 lipoprotein	(24)3 STT	(41)2 after	(58)2 molecular
(8)8 back	(25)3 concentrations	(42)2 areas	(59)2 oral
(9)8 birth	(26)3 educational	(43)2 at	(60)2 pH
(10)8 dose	(27)3 features	(44)2 bioavailability	(61)2 peer
(11)7 in	(28)3 risk	(45)2 body	(62)2 population
(12)7 level	(29)3 serum	(46)2 cancer	(63)2 radiation
(13)6 birthweight	(30)3 shear	(47)2 children	(64)2 resilience
(14)5 but	(31)3 tumours	(48)2 coverage	(65)2 running
(15)4 as	(32)3 vagal	(49)2 degree	(66)2 sensitivity
(16)4 carbon	(33)3 water	(50)2 density	(67)2 settings
(17)4 income	(34)3 whole-body	(51)2 education	(68)2 temperature

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--- WordNet output for low --- =>安い, 低いところ, 卑劣に, 粗食で, 低い(もの), 弱い, 粗末な, 乏しい, 衿ぐりが深い, 建物の低い, 下劣な, 低級な Overview of noun low The noun low has 4 senses (no senses from tagged texts) 1. low, depression -- (an air mass of lower pressure; often brings precipitation; "a low moved in over night bringing sleet and snow") 2. Low, David Low, Sir David Low, Sir David Alexander Cecil Low -- (British political cartoonist (born in New Zealand) who created the character Colonel Blimp (1891-1963)) 3. low -- (a low level or position or degree; "the stock market fell to a new low") 4. first gear, first, low gear, low -- (the lowest forward gear ratio in the gear box of a motor vehicle; used to start a car moving) Overview of verb low The verb low has 1 sense (no senses from tagged texts) 1. moo, low -- (make a low noise, characteristic of bovines) Overview of adj low The adj low has 10 senses (first 6 from tagged texts) 1. (55) low -- (less than normal in degree or intensity or amount; "low prices"; "the reservoir is low") 2. (23) low -- (literal meanings; being at or having a relatively small elevation or upward extension; "low ceilings"; "low clouds"; "low hills"; "the sun is low"; "low furniture"; "a low bow") 3. (11) low, low-toned -- (very low in volume; "a low murmur"; "the low-toned murmur of the surf") 4. (6) low -- (unrefined in character; "low comedy") 5. (4) low, low-pitched -- (used of sounds and voices; low in pitch or frequency) 6. (3) abject, low, low-down, miserable, scummy, scurvy -- (of the most contemptible kind; "abject cowardice"; "a low stunt to pull"; "a low-down sneak"; "his miserable treatment of his family"; "You miserable skunk!"; "a scummy rabble"; "a scurvy trick") 7. humble, low, lowly, modest, small -- (low or inferior in station or quality; "a humble cottage"; "a lowly parish priest"; "a modest man of the people"; "small beginnings") 8. depleted, low -- (no longer sufficient; "supplies are low"; "our funds are depleted") 9. broken, crushed, humbled, humiliated, low -- (subdued or brought low in condition or status; "brought low"; "a broken man"; "his broken spirit") 10. gloomy, grim, blue, depressed, dispirited, down, downcast, downhearted, down in the mouth, low, low-spirited -- (filled with melancholy and despondency ; "gloomy at the thought of what he had to face"; "gloomy predictions"; "a gloomy silence"; "took a grim view of the economy"; "the darkening mood"; "lonely and blue in a strange city"; "depressed by the loss of his job"; "a dispirited and resigned expression on her face"; "downcast after his defeat"; "feeling discouraged and downhearted") Overview of adv low The adv low has 1 sense (first 1 from tagged texts) 1. (3) low -- (in a low position; near the ground; "the branches hung low") --- WordNet end ---