ELIZA

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611425 occurrences (No.13 in the rank) during 5 years in the PubMed. [cache]

15) A significant increase in DNA damage was also observed at all concentrations of ITO by the Comet assay.

--- ABSTRACT ---

PMID:24337653 DOI:10.1007/s10616-013-9673-0

2015 Cytotechnology

* Genotoxicity of indium tin oxide by Allium and Comet tests.

- Genotoxic effects of indium tin oxide (ITO) were investigated on root cells of Allium cepa by employing both Allium and Comet assays. A. cepa roots were treated with the aqueous dispersions of ITO at 5 different concentrations (12.5, 25, 50, 75, and 100 ppm) for 4 h. Exposure of ITO significantly increased mitotic index, and total chromosomal aberrations by the Allium test. While chromosome laggards, stickiness, disturbed anaphase-telophase and anaphase bridges were observed in anaphase-telophase cells, c-metaphase and binuclear cells were observed in other cells. A significant increase in DNA damage was also observed at all concentrations of ITO by the Comet assay. These results indicate that ITO exhibits genotoxic activity in A. cepa root meristematic cells.

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(1)259 in	(7)6 during	(13)3 drug	(19)2 ROM
(2)55 the	(8)5 was	(14)3 from	(20)2 between
(3)36 of	(9)5 with	(15)3 or	(21)2 chlamydia
(4)10 null	(10)4 life	(16)3 susceptibility	(22)2 could
(5)7 physical	(11)3 at	(17)3 their	(23)2 observed
(6)6 and	(12)3 awareness	(18)2 (P	(24)2 our

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--- WordNet output for increase --- =>大きくなる, を増す, 増大させる, 強まる, 増加, 増える, 増やす Overview of noun increase The noun increase has 5 senses (first 5 from tagged texts) 1. (49) addition, increase, gain -- (a quantity that is added; "there was an addition to property taxes this year"; "they recorded the cattle's gain in weight over a period of weeks") 2. (21) increase -- (a change resulting in an increase; "the increase is scheduled for next month") 3. (7) increase, increment, growth -- (a process of becoming larger or longer or more numerous or more important; "the increase in unemployment"; "the growth of population") 4. (3) increase, increment -- (the amount by which something increases; "they proposed an increase of 15 percent in the fare") 5. (3) increase, step-up -- (the act of increasing something; "he gave me an increase in salary") Overview of verb increase The verb increase has 2 senses (first 2 from tagged texts) 1. (86) increase -- (become bigger or greater in amount; "The amount of work increased") 2. (61) increase -- (make bigger or more; "The boss finally increased her salary"; "The university increased the number of students it admitted") --- WordNet end ---