ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for higher out of >500 occurrences
487192 occurrences (No.29 in the rank) during 5 years in the PubMed. [no cache] 500 found
320) Results showed that proliferating PC12 cells secreted a higher quantity of dopamine on fibres with respect to control cultures and as a result, a possible use of PHB fibres was considered for cell transplantation in the central nervous system when local production of dopamine is impaired.
--- ABSTRACT ---
PMID:23086861 DOI:10.1002/term.1623
2015 Journal of tissue engineering and regenerative medicine
* PC12 neuron-like cell response to electrospun poly( 3-hydroxybutyrate) substrates.
- In the last decade, the importance of topographic properties of extracellular environments has been shown to be essential to addressing cell response, especially when replacing damaged tissues with functional constructs obtained in vitro. In the current study, densely packed sub-micron poly(3-hydroxybutyrate) (PHB) fibres were electrospun with random and parallel orientations. PC12 pheochromocytoma cells that mimic central dopaminergic neurons and represent a model for neuronal differentiation were cultured on collagen-coated fibres to evaluate cell response dependence on substrate topography. Cell adhesion, viability and proliferation, as well as dopamine production were evaluated after three days since seeding. Cell differentiation was examined in terms of neurite number, orientation and length 6 days after administration of nerve growth factor (NGF). Results showed that proliferating PC12 cells secreted a higher quantity of dopamine on fibres with respect to control cultures and as a result, a possible use of PHB fibres was considered for cell transplantation in the central nervous system when local production of dopamine is impaired. Differentiated PC12 cells were characterized by highly aligned and longer neurites on parallel PHB fibres with respect to random fibres, thereby demonstrating the suitability of parallel PHB fibres for further studies in peripheral nervous system regeneration.
--- ABSTRACT END ---
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(1)69 in (17)3 body (33)2 by (49)2 infant
(2)63 than (18)3 fatalism (34)2 concentrations (50)2 initial
(3)21 levels (19)3 likelihood (35)2 coverage (51)2 mean
(4)17 risk (20)3 odds (36)2 degree (52)2 order
(5)10 level (21)3 on (37)2 different (53)2 physiological
(6)9 among (22)3 quality (38)2 dose (54)2 probability
(7)8 for (23)2 (odds (39)2 doses (55)2 quantity
(8)6 rates (24)2 *null* (40)2 drug (56)2 rate
(9)5 cell (25)2 AT (41)2 during (57)2 relative
(10)5 potency (26)2 MTBS (42)2 education (58)2 revision
(11)5 scores (27)2 RDW (43)2 education, (59)2 sensitivity
(12)4 compared (28)2 abstinence (44)2 expectations (60)2 stress
(13)4 number (29)2 adjusted (45)2 expression (61)2 to
(14)4 prevalence (30)2 amount (46)2 frequency (62)2 total
(15)3 (P (31)2 birth (47)2 incidence (63)2 values
(16)3 amounts (32)2 blood (48)2 individual

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--- WordNet output for higher --- =>幹部, おえら方 Overview of adj higher The adj higher has 2 senses (first 2 from tagged texts) 1. (10) higher -- (advanced in complexity or elaboration; "higher finance"; "higher mathematics") 2. (1) higher -- (of education beyond the secondary level; "higher education"; "higher learning") Overview of adj high The adj high has 7 senses (first 5 from tagged texts) 1. (134) high -- (greater than normal in degree or intensity or amount; "a high temperature"; "a high price"; "the high point of his career"; "high risks"; "has high hopes"; "the river is high"; "he has a high opinion of himself") 2. (51) high -- ((literal meaning) being at or having a relatively great or specific elevation or upward extension (sometimes used in combinations like `knee-high'); "a high mountain"; "high ceilings"; "high buildings"; "a high forehead"; "a high incline"; "a foot high") 3. (10) eminent, high -- (standing above others in quality or position; "people in high places"; "the high priest"; "eminent members of the community") 4. (7) high, high-pitched -- (used of sounds and voices; high in pitch or frequency) 5. (2) high, in high spirits -- (happy and excited and energetic) 6. gamey, gamy, high -- ((used of the smell of meat) smelling spoiled or tainted) 7. high, mellow -- (slightly and pleasantly intoxicated from alcohol or a drug (especially marijuana)) --- WordNet end ---