kwic
higher
higher
right
off
ON
300
1
100
500
strict
ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -
return
kwic search for higher out of >500 occurrences
487192 occurrences (No.29 in the rank) during 5 years in the PubMed. [cache]
--- ABSTRACT ---
--- ABSTRACT END ---
[frequency of next (right) word to higher]
487192 occurrences (No.29 in the rank) during 5 years in the PubMed. [cache]
| 300) After an incubation period of 2 weeks, cells present in silica-containing hydrogels showed a significantly higher expression of the genes encoding the cytokine BMP-2, the major fibrillar structural protein collagen 1 and likewise of carbonic anhydrase. |
| PMID:23585362 DOI:10.1002/term.1745 |
| 2015 Journal of tissue engineering and regenerative medicine |
| * Development of a morphogenetically active scaffold for three-dimensional growth of bone cells: biosilica-alginate hydrogel for SaOS-2 cell cultivation. |
| - Polymeric silica is formed from ortho-silicate during a sol-gel formation process, while biosilica is the product of an enzymatically driven bio-polycondensation reaction. Both polymers have recently been described as a template that induces an increased expression of the genes encoding bone morphogenetic protein 2 (BMP-2) and osteoprotegerin in osteoblast-related SaOS-2 cells; simultaneously or subsequently the cells respond with enhanced hydroxyapatite formation. In order to assess whether the biocompatible polymeric silica/biosilica can serve as a morphogenetically active matrix suitable for three-dimensional (3D) cell growth, or even for 3D cell bioprinting, SaOS-2 cells were embedded into a Na-alginate-based hydrogel. Four different gelatinous hydrogel matrices were used for suspending SaOS-2 cells: (a) the hydrogel alone; (b) the hydrogel with 400 μM ortho-silicate; (c) the hydrogel supplemented with 400 μM ortho-silicate and recombinant silicatein to allow biosilica synthesis to occur; and (d) the hydrogel with ortho-silicate and BSA. The SaOS-2 cells showed an increased growth if silica/biosilica components were present in the hydrogel. Likewise intensified was the formation of hydroxyapatite nodules in the silica-containing hydrogels. After an incubation period of 2 weeks, cells present in silica-containing hydrogels showed a significantly higher expression of the genes encoding the cytokine BMP-2, the major fibrillar structural protein collagen 1 and likewise of carbonic anhydrase. It is concluded that silica, and to a larger extent biosilica, retains its morphogenetic/osteogenic potential after addition to Na-alginate-based hydrogels. This property might qualify silica hydrogels to be also used as a matrix for 3D cell printing. |
[
right
kwic]
(1)69  in |
(17)3 body |
(33)2 by |
(49)2 infant |
| (2)63 than |
(18)3 fatalism |
(34)2 concentrations |
(50)2 initial |
| (3)21 levels |
(19)3 likelihood |
(35)2 coverage |
(51)2 mean |
| (4)17 risk |
(20)3 odds |
(36)2 degree |
(52)2 order |
| (5)10 level |
(21)3 on |
(37)2 different |
(53)2 physiological |
| (6)9 among |
(22)3 quality |
(38)2 dose |
(54)2 probability |
| (7)8 for |
(23)2 (odds |
(39)2 doses |
(55)2 quantity |
| (8)6 rates |
(24)2 *null* | (40)2 drug |
(56)2 rate |
| (9)5 cell |
(25)2 AT |
(41)2 during |
(57)2 relative |
| (10)5 potency |
(26)2 MTBS |
(42)2 education |
(58)2 revision |
| (11)5 scores |
(27)2 RDW |
(43)2 education, |
(59)2 sensitivity |
| (12)4 compared |
(28)2 abstinence |
(44)2 expectations |
(60)2 stress |
| (13)4 number |
(29)2 adjusted |
(45)2 expression |
(61)2 to |
| (14)4 prevalence |
(30)2 amount |
(46)2 frequency |
(62)2 total |
| (15)3 (P |
(31)2 birth |
(47)2 incidence |
(63)2 values |
| (16)3 amounts |
(32)2 blood |
(48)2 individual |
add keyword
--- WordNet output for higher ---