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636281 occurrences (No.11 in the rank) during 5 years in the PubMed. [no cache]
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96) Data showed a significant increase in the levels of total cholesterol (TC), triglycerides (TGs), low-density lipoprotein cholesterol (LDL-C), 17 beta hydroxysteroid dehydrogenase (17 β HSD), testicular catalase and malondialdehyde (MDA) in G2 when compared with G1, whereas high-density lipoprotein cholesterol (HDL-C), serum testosterone, testicular 17 ketosteroid reductase (17 KSR), total thiol and glutathione-S-transferase (GST) data showed a significant decrease in G2 when compared with G1.
* Protective role of L-carnitine and vitamin E on the testis of atherosclerotic rats.
- Atherosclerosis is a condition caused by lipid build-up and inflammation in the arteries, so hyperlipidemia is the major reason for atherosclerosis. Testis was found to be negatively affected by hyperlipidemia which leads to its impaired functions. Vitamin E and l-carnitine have well-known lipid-lowering and antioxidative activities. Triton WR 1339 is a non-ionic detergent, which induces severe hyperlipidemia by inhibition of lipoprotein lipase. The present study evaluates the protective role of vitamin E and l-carnitine on the testis in atherosclerosis and detects the most effective choice for protection against atherosclerosis; vitamin E, l-carnitine or a combination of both. A total of 80 albino male rats were divided into eight groups (10 rats for each group): control (G1), triton (G2), l-carnitine (G3), triton + l-carnitine (G4), vitamin E (G5), triton + vitamin E (G6), l-carnitine + vitamin E (G7) and triton + l-carnitine + vitamin E (G8). Data showed a significant increase in the levels of total cholesterol (TC), triglycerides (TGs), low-density lipoprotein cholesterol (LDL-C), 17 beta hydroxysteroid dehydrogenase (17 β HSD), testicular catalase and malondialdehyde (MDA) in G2 when compared with G1, whereas high-density lipoprotein cholesterol (HDL-C), serum testosterone, testicular 17 ketosteroid reductase (17 KSR), total thiol and glutathione-S-transferase (GST) data showed a significant decrease in G2 when compared with G1. Treatment with l-carnitine or/and vitamin E helps in improving the adverse effect of triton; also the histological changes confirm this finding. So the present study recommends all people to include l-carnitine and vitamin E in their diet to be protected against atherosclerosis.
=>1.高いところにある, 高い, 高さが〜の, 高貴な, 高く, 高額の, 興奮状態の, 2.高い所, 高水準
Overview of noun high
The noun high has 7 senses (first 1 from tagged texts)
1. (5) high -- (a lofty level or position or degree; "summer temperatures reached an all-time high")
2. high -- (an air mass of higher than normal pressure; "the east coast benefits from a Bermuda
high")
3. high -- (a state of sustained elation; "I'm on a permanent high these days")
4. high -- (a state of altered consciousness induced by alcohol or narcotics; "they took drugs to
get a high on")
5. high, heights -- (a high place; "they stood on high and observed the countryside"; "he doesn't
like heights")
6. senior high school, senior high, high, highschool, high school -- (a public secondary school
usually including grades 9 through 12; "he goes to the neighborhood highschool")
7. high gear, high -- (a forward gear with a gear ratio that gives the greatest vehicle velocity for
a given engine speed)
Overview of adj high
The adj high has 7 senses (first 5 from tagged texts)
1. (134) high -- (greater than normal in degree or intensity or amount; "a high temperature"; "a
high price"; "the high point of his career"; "high risks"; "has high hopes"; "the river is high";
"he has a high opinion of himself")
2. (51) high -- ((literal meaning) being at or having a relatively great or specific elevation or
upward extension (sometimes used in combinations like `knee-high'); "a high mountain"; "high
ceilings"; "high buildings"; "a high forehead"; "a high incline"; "a foot high")
3. (10) eminent, high -- (standing above others in quality or position; "people in high places";
"the high priest"; "eminent members of the community")
4. (7) high, high-pitched -- (used of sounds and voices; high in pitch or frequency)
5. (2) high, in high spirits -- (happy and excited and energetic)
6. gamey, gamy, high -- ((used of the smell of meat) smelling spoiled or tainted)
7. high, mellow -- (slightly and pleasantly intoxicated from alcohol or a drug (especially
marijuana))
Overview of adv high
The adv high has 4 senses (first 2 from tagged texts)
1. (9) high, high up -- (at a great altitude; "he climbed high on the ladder")
2. (2) high -- (in or to a high position, amount, or degree; "prices have gone up far too high")
3. high, richly, luxuriously -- (in a rich manner; "he lives high")
4. high -- (far up toward the source; "he lives high up the river")
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