* Flow-cytometric detection of phenotypic aberrancies in canine small clear cell lymphoma.
- Histopathology and immunohistochemistry are mandatory to solve the differential between canine low-grade lymphoma and reactive hyperplasia. However, clinicians and owners often show reluctance toward these invasive tests. However, molecular biology techniques are still not sensitive and specific enough to be regarded as a reliable tool for final diagnosis. In humans, flow cytometry (FC) allows a definitive diagnosis of T-cell lymphoma based on high prevalence of antigen aberrancies. We describe here the immunophenotype of 26 cases of suspect canine small-clear cell lymphoma, determined by multi-colour FC. All cases showed antigen aberrancies and therefore neoplasia was always confirmed. As a consequence, we argue that the combined use of cytology and FC allows solving the differential diagnosis between small clear cell lymphoma and non-neoplastic reactive conditions when histopathology is not available. Further studies are needed to establish if any aberrancy can be considered indicative of specific histotypes.
=>1.高いところにある, 高い, 高さが〜の, 高貴な, 高く, 高額の, 興奮状態の, 2.高い所, 高水準
Overview of noun high
The noun high has 7 senses (first 1 from tagged texts)
1. (5) high -- (a lofty level or position or degree; "summer temperatures reached an all-time high")
2. high -- (an air mass of higher than normal pressure; "the east coast benefits from a Bermuda
high")
3. high -- (a state of sustained elation; "I'm on a permanent high these days")
4. high -- (a state of altered consciousness induced by alcohol or narcotics; "they took drugs to
get a high on")
5. high, heights -- (a high place; "they stood on high and observed the countryside"; "he doesn't
like heights")
6. senior high school, senior high, high, highschool, high school -- (a public secondary school
usually including grades 9 through 12; "he goes to the neighborhood highschool")
7. high gear, high -- (a forward gear with a gear ratio that gives the greatest vehicle velocity for
a given engine speed)
Overview of adj high
The adj high has 7 senses (first 5 from tagged texts)
1. (134) high -- (greater than normal in degree or intensity or amount; "a high temperature"; "a
high price"; "the high point of his career"; "high risks"; "has high hopes"; "the river is high";
"he has a high opinion of himself")
2. (51) high -- ((literal meaning) being at or having a relatively great or specific elevation or
upward extension (sometimes used in combinations like `knee-high'); "a high mountain"; "high
ceilings"; "high buildings"; "a high forehead"; "a high incline"; "a foot high")
3. (10) eminent, high -- (standing above others in quality or position; "people in high places";
"the high priest"; "eminent members of the community")
4. (7) high, high-pitched -- (used of sounds and voices; high in pitch or frequency)
5. (2) high, in high spirits -- (happy and excited and energetic)
6. gamey, gamy, high -- ((used of the smell of meat) smelling spoiled or tainted)
7. high, mellow -- (slightly and pleasantly intoxicated from alcohol or a drug (especially
marijuana))
Overview of adv high
The adv high has 4 senses (first 2 from tagged texts)
1. (9) high, high up -- (at a great altitude; "he climbed high on the ladder")
2. (2) high -- (in or to a high position, amount, or degree; "prices have gone up far too high")
3. high, richly, luxuriously -- (in a rich manner; "he lives high")
4. high -- (far up toward the source; "he lives high up the river")
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