ELIZA cgi-bash version rev. 1.90
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kwic search for high out of >500 occurrences
636281 occurrences (No.11 in the rank) during 5 years in the PubMed. [no cache]
500 found
215) The treatment of multiple myeloma has evolved significantly over the past 2 decades due to the use of high-dose chemotherapy and autologous stem cell transplantation, and the subsequent introduction of the immunomodulatory agents (thalidomide and lenalidomide) and the proteasome inhibitor (bortezomib).
- The treatment of multiple myeloma has evolved significantly over the past 2 decades due to the use of high-dose chemotherapy and autologous stem cell transplantation, and the subsequent introduction of the immunomodulatory agents (thalidomide and lenalidomide) and the proteasome inhibitor (bortezomib). The median overall survival of multiple myeloma patients has increased significantly with patients younger than age 50 years experiencing a 10-year survival rate of around 40%. However, despite the increased effectiveness of the first-line agents, the majority of patients will eventually relapse and become drug resistant. Promising novel therapies have recently emerged and are being used to treat relapsed and refractory patients. This review will cover the clinical data regarding these emergent therapies that include new generation of proteasome inhibitors (carfilzomib, ixazomib, oprozomib, and marizomib), immunomodulatory drugs (pomalidomide), monoclonal antibodies (elotuzumab and daratumumab), signal transduction modulator (perifosine), and histone deacetylase inhibitors (vorinostat and panobinostat).
=>1.高いところにある, 高い, 高さが〜の, 高貴な, 高く, 高額の, 興奮状態の, 2.高い所, 高水準
Overview of noun high
The noun high has 7 senses (first 1 from tagged texts)
1. (5) high -- (a lofty level or position or degree; "summer temperatures reached an all-time high")
2. high -- (an air mass of higher than normal pressure; "the east coast benefits from a Bermuda
high")
3. high -- (a state of sustained elation; "I'm on a permanent high these days")
4. high -- (a state of altered consciousness induced by alcohol or narcotics; "they took drugs to
get a high on")
5. high, heights -- (a high place; "they stood on high and observed the countryside"; "he doesn't
like heights")
6. senior high school, senior high, high, highschool, high school -- (a public secondary school
usually including grades 9 through 12; "he goes to the neighborhood highschool")
7. high gear, high -- (a forward gear with a gear ratio that gives the greatest vehicle velocity for
a given engine speed)
Overview of adj high
The adj high has 7 senses (first 5 from tagged texts)
1. (134) high -- (greater than normal in degree or intensity or amount; "a high temperature"; "a
high price"; "the high point of his career"; "high risks"; "has high hopes"; "the river is high";
"he has a high opinion of himself")
2. (51) high -- ((literal meaning) being at or having a relatively great or specific elevation or
upward extension (sometimes used in combinations like `knee-high'); "a high mountain"; "high
ceilings"; "high buildings"; "a high forehead"; "a high incline"; "a foot high")
3. (10) eminent, high -- (standing above others in quality or position; "people in high places";
"the high priest"; "eminent members of the community")
4. (7) high, high-pitched -- (used of sounds and voices; high in pitch or frequency)
5. (2) high, in high spirits -- (happy and excited and energetic)
6. gamey, gamy, high -- ((used of the smell of meat) smelling spoiled or tainted)
7. high, mellow -- (slightly and pleasantly intoxicated from alcohol or a drug (especially
marijuana))
Overview of adv high
The adv high has 4 senses (first 2 from tagged texts)
1. (9) high, high up -- (at a great altitude; "he climbed high on the ladder")
2. (2) high -- (in or to a high position, amount, or degree; "prices have gone up far too high")
3. high, richly, luxuriously -- (in a rich manner; "he lives high")
4. high -- (far up toward the source; "he lives high up the river")
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