ELIZA

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385944 occurrences (No.46 in the rank) during 5 years in the PubMed. [no cache] 500 found

68) A total of 28 rats were equally divided into four groups; the first group was kept as control.

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PMID:23552266 DOI:10.1177/0748233713483192

2015 Toxicology and industrial health

* Hesperidin protects brain and sciatic nerve tissues against cisplatin-induced oxidative, histological and electromyographical side effects in rats.

- In the present study, the beneficial effect of hesperidin (HP), a citrus flavonoid, on cisplatin (CP)-induced neurotoxicity was investigated. A total of 28 rats were equally divided into four groups; the first group was kept as control. In the second and third groups, CP and HP were given at the doses of 7 and 50 mg/kg/day, respectively. In the fourth group, CP and HP were given together at the same doses. The results indicated that although CP caused significant induction of lipid peroxidations and reduction in the antioxidant defense system potency in the brain and sciatic nerve, HP prevented these effects of CP. Besides, CP led to histopathological damage, mainly apoptosis, as well as electromyographical (EMG) changes in sciatic nerve. On the other hand, HP treatment reversed histopathological and EMG effects of CP. In conclusion, CP had severe dose-limiting neurotoxic effects and these effects of CP can be prevented by HP treatment. Thus, it appears that coadministration of HP with CP may be a useful approach to attenuate the negative effects of CP on the nervous system.

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(1)49 null	(15)7 received	(29)3 II	(44)2 difference
(2)33 was	(16)5 at	(30)3 after	(45)2 displayed
(3)29 and	(17)5 for	(31)3 comprised	(46)2 dynamics-based
(4)25 of	(18)5 the	(32)3 in	(47)2 exhibited
(5)16 compared	(19)5 to	(33)3 when	(48)2 however,
(6)12 A	(20)4 (p	(34)2 (30	(49)2 improved
(7)12 were	(21)4 B	(35)2 (n	(50)2 included
(8)11 discussions	(22)4 C	(37)2 B,	(51)2 intervention
(9)10 than	(23)4 differences	(38)2 III	(52)2 interventions
(10)9 I	(24)4 or	(39)2 V	(53)2 interviews
(11)8 had	(25)3 1,	(40)2 a	(54)2 patients
(12)8 showed	(26)3 2	(41)2 as	(55)2 presented
(13)8 with	(27)3 4	(42)2 contains	(56)2 that
(14)7 1	(28)3 A,	(43)2 demonstrated

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--- WordNet output for group --- =>一団にする, 集める, 分派, 集団, グループ, 分類する, 演奏家グループ, 集まる, 分ける Overview of noun group The noun group has 3 senses (first 2 from tagged texts) 1. (1345) group, grouping -- (any number of entities (members) considered as a unit) 2. (1) group, radical, chemical group -- ((chemistry) two or more atoms bound together as a single unit and forming part of a molecule) 3. group, mathematical group -- (a set that is closed, associative, has an identity element and every element has an inverse) Overview of verb group The verb group has 2 senses (first 2 from tagged texts) 1. (4) group -- (arrange into a group or groups; "Can you group these shapes together?") 2. (1) group, aggroup -- (form a group or group together) --- WordNet end ---