ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for expression of out of >500 occurrences
286252 occurrences (No.88 in the rank) during 5 years in the PubMed. [no cache] 500 found
26) First, oxygen availability and diffusion were investigated, using transgenic cell lines in which a hypoxia-responsive element drives expression of the green fluorescent protein gene.
--- ABSTRACT ---
PMID:23349072 DOI:10.1002/term.1654
2015 Journal of tissue engineering and regenerative medicine
* Monitoring nutrient transport in tissue-engineered grafts.
- Limited nutrient diffusion in three-dimensional (3D) constructs is a major concern in tissue engineering. Therefore, monitoring nutrient availability and diffusion within a scaffold is an important asset. Since nutrients come in various forms, we have investigated the diffusion of the oxygen, luciferin and dextran molecules within tissue-engineered constructs using optical imaging technologies. First, oxygen availability and diffusion were investigated, using transgenic cell lines in which a hypoxia-responsive element drives expression of the green fluorescent protein gene. Using confocal imaging, we observed oxygen limitation, starting at around 200 µm from the periphery in the context of agarose gel with 1 million CHO cells. Diffusion of luciferin was monitored real-time in agarose gels using a cell line in which the luciferase gene was driven by a constitutively active CMV promoter. Gel concentration affected the diffusion rate of luciferin. Furthermore, we assessed the diffusion rates of fluorescent dextran molecules of different molecular weights in biomaterials by fluorescence recovery after photobleaching (FRAP) and observed that diffusion depended on both molecular size and gel concentration. In conclusion, we have validated a set of efficient tools to investigate molecular diffusion of a range of molecules and to optimize biomaterials design in order to improve nutrient delivery.
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[frequency of next (right) word to expression of]
(1)55 the (15)3 key (29)2 P-selectin, (44)2 cell
(2)11 a (16)3 multiple (30)2 P2X3 (45)2 constitutively
(3)9 genes (17)3 ncRAN (32)2 Sema (46)2 hyaluronan
(4)8 several (18)3 nicotine-induced (33)2 Siglec-9 (47)2 imprinted
(5)6 miR-218 (19)3 nuclear (34)2 TAF4 (48)2 intercellular
(6)5 these (20)3 specific (35)2 Wnt (49)2 membrane
(7)4 VEGF (21)3 this (36)2 acetyl-CoA (50)2 miR-128
(8)4 first (22)2 AdipoR1 (37)2 adhesion (51)2 napsin
(9)4 matrix (23)2 Caspase (38)2 adiponectin (52)2 phosphorylated
(10)3 CYP1A1 (24)2 FBP1 (39)2 angiogenic (53)2 piRNA-823
(11)3 DNMT1 (25)2 GABAA (40)2 anti-apoptotic (54)2 pro-inflammatory
(12)3 all (26)2 GLP-1R (41)2 b-FGF, (55)2 some
(13)3 cardiac (27)2 Ki-67, (42)2 c-Myc (56)2 three
(14)3 integrin (28)2 LOX-1 (43)2 cartilage

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--- WordNet output for expression --- =>表現すること, 式, 表現, 表示, 言い回し, 表現法, 表情 Overview of noun expression The noun expression has 9 senses (first 6 from tagged texts) 1. (23) expression, look, aspect, facial expression, face -- (the feelings expressed on a person's face; "a sad expression"; "a look of triumph"; "an angry face") 2. (18) expression, manifestation, reflection, reflexion -- (expression without words; "tears are an expression of grief"; "the pulse is a reflection of the heart's condition") 3. (15) expression, verbal expression, verbalism -- (the communication (in speech or writing) of your beliefs or opinions; "expressions of good will"; "he helped me find verbal expression for my ideas"; "the idea was immediate but the verbalism took hours") 4. (5) saying, expression, locution -- (a word or phrase that particular people use in particular situations; "pardon the expression") 5. (4) formulation, expression -- (the style of expressing yourself; "he suggested a better formulation"; "his manner of expression showed how much he cared") 6. (4) formula, expression -- (a group of symbols that make a mathematical statement) 7. expression -- ((genetics) the process of expressing a gene) 8. construction, grammatical construction, expression -- (a group of words that form a constituent of a sentence and are considered as a single unit; "I concluded from his awkward constructions that he was a foreigner") 9. expression -- (the act of forcing something out by squeezing or pressing; "the expression of milk from her breast") --- WordNet end ---