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return kwic search for due to out of >500 occurrences
319715 occurrences (No.67 in the rank) during 5 years in the PubMed. [cache]
282) However, muscle weakness and the disability progressed due to steroid myopathy, and subsequent oral intake became impossible because of swallowing disturbance in these two patients.
--- ABSTRACT ---
PMID:24533547 DOI:10.3109/14397595.2013.874750
2015 Modern rheumatology
* Two cases of refractory polymyositis accompanied with steroid myopathy.
- Polymyositis (PM) is an inflammatory muscle disease characterized by chronic inflammation in skeletal muscle. Although most patients with PM respond to corticosteroids, some cases show an unsatisfactory response and other therapeutic options must be considered. Furthermore, glucocorticosteroid (GC) toxicity leads to a significant disability known as steroid myopathy, particularly in elderly patients. Here we report two patients with refractory PM. Combined treatment with high-dose GCs, tacrolimus, and intravenous immunoglobulin resulted in beneficial effects against myositis. However, muscle weakness and the disability progressed due to steroid myopathy, and subsequent oral intake became impossible because of swallowing disturbance in these two patients. Nutritional intervention, including branched-chain amino acids (BCAAs) and rehabilitation, was undertaken in addition to treatment against myositis. These treatments finally improved the muscle weakness and activities of daily living, and the two patients were discharged after recovery. The high-dose GC treatment caused elevation of serum levels of amino acids, including BCAAs, but these amino acids subsequently declined during BCAA replacement therapy. These findings suggest that the catabolic effects of the glucocorticoid treatment impair the balance of amino acids, including BCAAs, within the muscle, leading to steroid myopathy.
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[frequency of next (right) word to due to]
(1)115 the (10)4 insufficient (19)2 cardiac (28)2 pannus
(2)30 its (11)3 changes (20)2 common (29)2 potential
(3)30 their (12)3 increased (21)2 condom (30)2 previous
(4)20 a (13)3 low (22)2 environmental (31)2 primary
(5)9 an (14)3 multiple (23)2 extreme (32)2 progressive
(6)5 limited (15)3 poor (24)2 inadequate (33)2 prolonged
(7)4 differences (16)3 possible (25)2 inflammation (34)2 similarities
(8)4 different (17)2 abnormal (26)2 lack (35)2 some
(9)4 high (18)2 anthropogenic (27)2 major

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--- WordNet output for due --- =>1.予定の, 支払期日がきて, 当然支払われるべき, 2.支払[提出]期日, 満期日, 会費 Overview of noun due The noun due has 2 senses (first 1 from tagged texts) 1. (4) due -- (that which is deserved or owed; "give the devil his due") 2. due -- (a payment that is due (e.g., as the price of membership); "the society dropped him for non-payment of dues") Overview of adj due The adj due has 4 senses (first 2 from tagged texts) 1. (6) due -- (owed and payable immediately or on demand; "payment is due") 2. (1) due -- (scheduled to arrive; "the train is due in 15 minutes") 3. due -- (suitable to or expected in the circumstances; "all due respect"; "due cause to honor them"; "a long due promotion"; "in due course"; "due esteem"; "exercising due care") 4. ascribable, due, imputable, referable -- (capable of being assigned or credited to; "punctuation errors ascribable to careless proofreading"; "the cancellation of the concert was due to the rain"; "the oversight was not imputable to him") Overview of adv due The adv due has 1 sense (no senses from tagged texts) 1. due -- (directly or exactly; straight; "went due North") --- WordNet end ---