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27) Since then, anticoagulant effect of polymyxin B is most likely due to the binding to negatively charged phospholipids, preventing formation of coagulation complexes.
2015 Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
* Inhibition of Binding of β2-Glycoprotein 1 to Phosphatidylserine by Polymyxin B, a Lupus-Like Anticoagulant.
- Polymyxin B is a cationic peptide that inhibits phospholipid-dependent coagulation tests including activated partial thromboplastin time and to a lesser degree prothrombin time. Thrombin clotting time is insensitive to polymyxin B. β2-glycoprotein 1 (β2GP1) is a cofactor of antiphospholipid antibodies. Antiphospholipid autoantibodies also poses lupus anticoagulant activity through interactions with β2GP1. Using affinity chromatography, polymyxin B can effectively decrease the binding of β2GP1 to immobilize phosphatidylserine. Since then, anticoagulant effect of polymyxin B is most likely due to the binding to negatively charged phospholipids, preventing formation of coagulation complexes.
=>1.予定の, 支払期日がきて, 当然支払われるべき, 2.支払[提出]期日, 満期日, 会費
Overview of noun due
The noun due has 2 senses (first 1 from tagged texts)
1. (4) due -- (that which is deserved or owed; "give the devil his due")
2. due -- (a payment that is due (e.g., as the price of membership); "the society dropped him for
non-payment of dues")
Overview of adj due
The adj due has 4 senses (first 2 from tagged texts)
1. (6) due -- (owed and payable immediately or on demand; "payment is due")
2. (1) due -- (scheduled to arrive; "the train is due in 15 minutes")
3. due -- (suitable to or expected in the circumstances; "all due respect"; "due cause to honor
them"; "a long due promotion"; "in due course"; "due esteem"; "exercising due care")
4. ascribable, due, imputable, referable -- (capable of being assigned or credited to; "punctuation
errors ascribable to careless proofreading"; "the cancellation of the concert was due to the rain";
"the oversight was not imputable to him")
Overview of adv due
The adv due has 1 sense (no senses from tagged texts)
1. due -- (directly or exactly; straight; "went due North")
--- WordNet end ---