ELIZA

return kwic search for disease out of >500 occurrences
422715 occurrences (No.39 in the rank) during 5 years in the PubMed. [no cache] 500 found

337) Median disease-free interval (DFI) and median survival time (MST) were evaluated as secondary endpoints.

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PMID:23663234 DOI:10.1111/vco.12040

2015 Veterinary and comparative oncology

* Adjuvant therapy with carboplatin and pamidronate for canine appendicular osteosarcoma.

- Amputation and chemotherapy are the mainstay of treatment for canine appendicular osteosarcoma (OSA). In vitro studies have demonstrated anti-tumour activity of pamidronate against canine OSA. The purpose of this study was to assess the safety of adding pamidronate to standard post-operative carboplatin chemotherapy in 17 dogs with appendicular OSA treated with limb amputation. Median disease-free interval (DFI) and median survival time (MST) were evaluated as secondary endpoints. Incidence of side effects and treatment outcomes were compared to 14 contemporary control patients treated with carboplatin alone. There were no identified side effects to the pamidronate treatment. The median DFI for the study group was 185 days compared to 172 days for the control group (P = 0.90). The MST of the study group was 311 days compared to 294 days for the control group (P = 0.89). Addition of pamidronate to carboplatin chemotherapy for the treatment of canine appendicular OSA is safe and does not impair efficacy of standard carboplatin treatment.

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(1)100 null	(17)4 (PD)	(33)3 to	(49)2 condition,
(2)39 and	(18)4 activity	(34)2 (CHD)	(50)2 development
(3)16 is	(19)4 outcome	(35)2 (COPD)	(51)2 interval
(4)13 in	(20)4 severity,	(36)2 (CVD),	(52)2 many
(5)12 of	(21)4 the	(37)2 (GERD)	(53)2 multi-sectoral
(6)9 (FMD)	(22)4 who	(38)2 (LSD)	(54)2 on
(7)8 risk	(23)3 (CAD)	(39)2 (SC)	(55)2 onset
(8)7 severity	(24)3 compared	(40)2 Control	(56)2 onset,
(9)6 progression	(25)3 control	(41)2 activity,	(57)2 outbreaks
(10)6 that	(26)3 course	(42)2 are	(58)2 patterns
(11)6 was	(27)3 free	(43)2 as	(59)2 phobia
(12)5 (CVD)	(28)3 has	(44)2 associated	(60)2 prevention
(13)5 or	(29)3 management	(45)2 burden	(61)2 processes
(14)5 state	(30)3 may	(46)2 by	(62)2 progression,
(15)4 (AD)	(31)3 patients	(47)2 can	(63)2 surveillance
(16)4 (HD)	(32)3 states	(48)2 characterized	(64)2 usually

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--- WordNet output for disease --- =>病気, 病弊, 精神の退廃 Overview of noun disease The noun disease has 1 sense (first 1 from tagged texts) 1. (26) disease -- (an impairment of health or a condition of abnormal functioning) --- WordNet end ---