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383) In order to estimate the anatomical origin of the obtained data, the maximum tissue volume of influence (TVImax) for a microdialysis catheter was simulated using the finite element method.
2015 Computer methods in biomechanics and biomedical engineering
* A diffusion tensor-based finite element model of microdialysis in the deep brain.
- Microdialysis of the basal ganglia was recently used to study neurotransmitter levels in relation to deep brain stimulation. In order to estimate the anatomical origin of the obtained data, the maximum tissue volume of influence (TVImax) for a microdialysis catheter was simulated using the finite element method. This study investigates the impact of brain heterogeneity and anisotropy on the TVImax using diffusion tensor imaging (DTI) to create a second-order tensor model of the basal ganglia. Descriptive statistics showed that the maximum migration distance for neurotransmitters varied by up to 55% (n = 98,444) for DTI-based simulations compared with an isotropic reference model, and the anisotropy differed between different targets in accordance with theory. The size of the TVImax was relevant in relation to the size of the anatomical structures of interest, and local tissue properties should be accounted for when relating microdialysis data to their anatomical targets.
=>データ, 資料
Overview of noun data
The noun data has 1 sense (first 1 from tagged texts)
1. (76) data, information -- (a collection of facts from which conclusions may be drawn;
"statistical data")
Overview of noun datum
The noun datum has 1 sense (first 1 from tagged texts)
1. (5) datum, data point -- (an item of factual information derived from measurement or research)
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