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505522 occurrences (No.25 in the rank) during 5 years in the PubMed. [cache]
76) We observed the specific attachment of the functionalized gold plasmonic nanoparticles (AuNPs) targeting CD44(+) human breast cancer cells by conventional and by proposed hyperspectral darkfield microscopy.
* Hyperspectral darkfield microscopy of PEGylated gold nanoparticles targeting CD44-expressing cancer cells.
- We present a new hyperspectral darkfield imaging system with a scanned broadband supercontinuum light source. We observed the specific attachment of the functionalized gold plasmonic nanoparticles (AuNPs) targeting CD44(+) human breast cancer cells by conventional and by proposed hyperspectral darkfield microscopy. This wide-field and low phototoxic hyperspectral imaging system has been successful for performing spectral three-dimensional (3D) localization and spectroscopic identification of CD44-targeted PEGylated AuNPs in fixed cell preparations. Such spatial and spectral information is essential for the improvement of nanoplasmonic-based imaging, disease detection and treatment in complex biological environment. Presented system capability for 3D NP tracking will also enable investigation of specific sub-cellular activity with the use of NPs as spectral sensors.
=>【病名】がん, 悪性腫瘍(しゅよう), がん腫, 社会悪, 癌
Overview of noun cancer
The noun cancer has 5 senses (first 1 from tagged texts)
1. (15) cancer, malignant neoplastic disease -- (any malignant growth or tumor caused by abnormal
and uncontrolled cell division; it may spread to other parts of the body through the lymphatic
system or the blood stream)
2. Cancer, Crab -- ((astrology) a person who is born while the sun is in Cancer)
3. Cancer -- (a small zodiacal constellation in the northern hemisphere; between Leo and Gemini)
4. Cancer, Cancer the Crab, Crab -- (the fourth sign of the zodiac; the sun is in this sign from
about June 21 to July 22)
5. Cancer, genus Cancer -- (type genus of the family Cancridae)
--- WordNet end ---