ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for cancer out of >500 occurrences
505522 occurrences (No.25 in the rank) during 5 years in the PubMed. [no cache] 500 found
13) Genetic testing of the family members indicated that the same double heterozygosity for BRCA1 and BRCA2 genes was transmitted to the paternal cousin, and the same BRCA2 mutation to the younger sister with bilateral breast cancer, younger brother with stomach cancer, and proband's son and daughter without cancer.
--- ABSTRACT ---
PMID:23242612 DOI:10.1007/s12282-012-0432-4
2015 Breast cancer (Tokyo, Japan)
* A case of familial breast cancer with double heterozygosity for BRCA1 and BRCA2 genes.
- We report an extremely rare case of familial breast cancer with deleterious germline mutations in both BRCA1 and BRCA2 genes, of which, to date, no such case has been reported among Japanese breast/ovarian cancer patients. Genetic testing of the family members indicated that the same double heterozygosity for BRCA1 and BRCA2 genes was transmitted to the paternal cousin, and the same BRCA2 mutation to the younger sister with bilateral breast cancer, younger brother with stomach cancer, and proband's son and daughter without cancer. Immunohistochemical analysis of BRCA protein expression was performed using breast cancer tissues from the proband with double heterozygosity for BRCA1 and BRCA2 genes and from her sibling without BRCA1 mutation but with BRCA2 mutation. There was no staining of either BRCA in the proband and no staining of BRCA2 in the sibling.
--- ABSTRACT END ---
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[frequency of next (right) word to cancer]
(1)65 *null* (14)6 therapy (27)3 of (40)2 epigenetics
(2)48 cells (15)6 tissues (28)3 patients, (41)2 growth
(3)33 and (16)5 cells, (29)3 research (42)2 initiation
(4)32 cell (17)5 progression (30)3 was (43)2 prevention
(5)23 patients (18)5 registries (31)2 (GC) (44)2 registry
(6)15 in (19)4 at (32)2 biology (45)2 study
(7)14 is (20)4 deaths (33)2 but (46)2 susceptibility
(8)12 risk (21)4 has (34)2 can (47)2 than
(9)12 screening (22)4 mortality (35)2 care (48)2 treated
(10)12 stem (23)3 (CRC) (36)2 development (49)2 treatment
(11)9 survivors (24)3 as (37)2 diagnostic (50)2 using
(12)7 with (25)3 cases (38)2 drug
(13)6 are (26)3 metabolism (39)2 drugs

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--- WordNet output for cancer --- =>【病名】がん, 悪性腫瘍(しゅよう), がん腫, 社会悪, 癌 Overview of noun cancer The noun cancer has 5 senses (first 1 from tagged texts) 1. (15) cancer, malignant neoplastic disease -- (any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream) 2. Cancer, Crab -- ((astrology) a person who is born while the sun is in Cancer) 3. Cancer -- (a small zodiacal constellation in the northern hemisphere; between Leo and Gemini) 4. Cancer, Cancer the Crab, Crab -- (the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22) 5. Cancer, genus Cancer -- (type genus of the family Cancridae) --- WordNet end ---