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- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

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346933 occurrences (No.53 in the rank) during 5 years in the PubMed. [cache]
271) However, the great need to estimate elastic modulus leads us to develop an alternative practical method, based on shear stress-strain, i.e.
--- ABSTRACT ---
PMID:24071531 DOI:10.1093/imammb/dqt020
2015 Mathematical medicine and biology : a journal of the IMA
* The invalidity of the Laplace law for biological vessels and of estimating elastic modulus from total stress vs. strain: a new practical method.
- There are strong medical motivations to measure changes in material properties of tubular organs, in vivo and in vitro. The current approach estimates hoop stress from intraluminal pressure using the Laplace law and identifies 'elastic modulus' as the slope of a curve fitted hoop stress plotted against strain data. We show that this procedure is fundamentally flawed because muscle and other soft tissue are closely incompressible, so that the total stress includes a volume-preserving material-dependent hydrostatic response that invalidates the method. Furthermore, we show that the Laplace law incorrectly estimates total stress in biological vessels. However, the great need to estimate elastic modulus leads us to develop an alternative practical method, based on shear stress-strain, i.e. insensitive to nonelastic response from incompressibility, but that uses the same measurement data as the current (incorrect) method. The individual material parameters in the underlying (unknown) constitutive relation combine into an effective shear modulus that is a true measure of elastic response, unaffected by incompressibility and without reference to the Laplace law. Furthermore, our effective shear modulus is determined directly as a function of deformation, rather than as the slope of a fitted curve. We validate our method by comparing effective shear moduli against exact shear moduli for four theoretical materials with different degrees of nonlinearity and numbers of material parameters. To further demonstrate applicability, we reanalyse an in vivo study with our new method and show that it resolves an inconsistent change in modulus with the current method.
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(1)142 the (8)4 data (15)2 clinical (22)2 partial
(2)40 a (9)4 our (16)2 combined (23)2 previous
(3)19 these (10)4 two (17)2 current (24)2 radiological
(4)9 their (11)3 16S (18)2 functional (25)2 sequences
(5)7 this (12)3 an (19)2 histological (26)2 shear
(6)5 its (13)2 all (20)2 interviews (27)2 small
(7)4 both (14)2 changes (21)2 morphology (28)2 surveys

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--- WordNet output for based --- =>に基づき Overview of verb base The verb base has 3 senses (first 1 from tagged texts) 1. (75) establish, base, ground, found -- (use as a basis for; found on; "base a claim on some observation") 2. base -- (situate as a center of operations; "we will base this project in the new lab") 3. free-base, base -- (use (purified cocaine) by burning it and inhaling the fumes) Overview of adj based The adj based has 2 senses (first 2 from tagged texts) 1. (3) based -- (having a base; "firmly based ice") 2. (1) based -- (having a base of operations (often used as a combining form); "a locally based business"; "an Atlanta-based company"; "carrier-based planes") --- WordNet end ---