ELIZA

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346933 occurrences (No.53 in the rank) during 5 years in the PubMed. [no cache] 500 found

250) However, despite progress in the understanding of FMF disease mechanisms during the past 15 years; the diagnosis is still based on clinical criteria.

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PMID:24424166 DOI:10.1016/j.autrev.2014.01.045

2015 Autoimmunity reviews

* Diagnostic criteria of familial Mediterranean fever.

- Familial Mediterranean fever (FMF) is the most prevalent monogenic autoinflammatory disease, mainly affecting ethnic groups living at Mediterranean basin. FMF is characterized by recurrent, self-limited episodes of fever and serositis. The diagnosis is difficult in the presence of atypical signs, which may result in significant delay in initiating treatment. As autoinflammatory diseases may have overlapping symptoms, strict diagnostic criteria are essential. Since the discovery that mutations in the gene MEFV underlie FMF, molecular genetic testing has been used as a diagnostic adjunct, especially in atypical cases. However, despite progress in the understanding of FMF disease mechanisms during the past 15 years; the diagnosis is still based on clinical criteria. Several sets of diagnostic criteria have been proposed and used. Existing diagnostic criteria should be modified to include genetic data, and need to be more widely validated.

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(1)142 the	(8)4 data	(15)2 clinical	(22)2 partial
(2)40 a	(9)4 our	(16)2 combined	(23)2 previous
(3)19 these	(10)4 two	(17)2 current	(24)2 radiological
(4)9 their	(11)3 16S	(18)2 functional	(25)2 sequences
(5)7 this	(12)3 an	(19)2 histological	(26)2 shear
(6)5 its	(13)2 all	(20)2 interviews	(27)2 small
(7)4 both	(14)2 changes	(21)2 morphology	(28)2 surveys

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--- WordNet output for based --- =>に基づき Overview of verb base The verb base has 3 senses (first 1 from tagged texts) 1. (75) establish, base, ground, found -- (use as a basis for; found on; "base a claim on some observation") 2. base -- (situate as a center of operations; "we will base this project in the new lab") 3. free-base, base -- (use (purified cocaine) by burning it and inhaling the fumes) Overview of adj based The adj based has 2 senses (first 2 from tagged texts) 1. (3) based -- (having a base; "firmly based ice") 2. (1) based -- (having a base of operations (often used as a combining form); "a locally based business"; "an Atlanta-based company"; "carrier-based planes") --- WordNet end ---