ELIZA

return kwic search for based out of >500 occurrences
404793 occurrences (No.42 in the rank) during 5 years in the PubMed. [no cache] 500 found

341) Silk fibroin-based scaffolds may be used to increase cell affinity to biomaterials and may be chemically modified to improve cell adhesion.

--- ABSTRACT ---

PMID:23592297 DOI:10.1002/term.1739

2015 Journal of tissue engineering and regenerative medicine

* Silk fibroin scaffolds enhance cell commitment of adult rat cardiac progenitor cells.

- The use of three-dimensional (3D) cultures may induce cardiac progenitor cells to synthesize their own extracellular matrix (ECM) and sarcomeric proteins to initiate cardiac differentiation. 3D cultures grown on synthetic scaffolds may favour the implantation and survival of stem cells for cell therapy when pharmacological therapies are not efficient in curing cardiovascular diseases and when organ transplantation remains the only treatment able to rescue the patient's life. Silk fibroin-based scaffolds may be used to increase cell affinity to biomaterials and may be chemically modified to improve cell adhesion. In the present study, porous, partially orientated and electrospun nanometric nets were used. Cardiac progenitor cells isolated from adult rats were seeded by capillarity in the 3D structures and cultured inside inserts for 21 days. Under this condition, the cells expressed a high level of sarcomeric and cardiac proteins and synthesized a great quantity of ECM. In particular, partially orientated scaffolds induced the synthesis of titin, which is a fundamental protein in sarcomere assembly.

--- ABSTRACT END ---

[
right
kwic]

[frequency of next (right) word to based]

(1)247 on	(10)3 approach	(19)2 chemotherapy	(28)2 physical
(2)10 method	(11)3 hydrogels	(20)2 computer-tailored	(29)2 rehabilitation
(3)10 therapies	(12)3 information	(21)2 financing	(30)2 retrospective
(4)5 cross-sectional	(13)3 study	(22)2 learning	(31)2 scaffolds
(5)5 upon	(14)3 techniques	(23)2 methods	(32)2 strategy
(6)4 survey	(15)3 therapeutic	(24)2 modelling	(33)2 studies
(7)4 tissue	(16)2 NPWT	(25)2 morphometry	(34)2 telephone
(8)3 CRT	(17)2 RUTF	(26)2 nutrient	(35)2 vaccination
(9)3 anti-bullying	(18)2 and	(27)2 palliative

add keyword

--- WordNet output for based --- =>に基づき Overview of verb base The verb base has 3 senses (first 1 from tagged texts) 1. (75) establish, base, ground, found -- (use as a basis for; found on; "base a claim on some observation") 2. base -- (situate as a center of operations; "we will base this project in the new lab") 3. free-base, base -- (use (purified cocaine) by burning it and inhaling the fumes) Overview of adj based The adj based has 2 senses (first 2 from tagged texts) 1. (3) based -- (having a base; "firmly based ice") 2. (1) based -- (having a base of operations (often used as a combining form); "a locally based business"; "an Atlanta-based company"; "carrier-based planes") --- WordNet end ---