ELIZA

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404793 occurrences (No.42 in the rank) during 5 years in the PubMed. [no cache] 500 found

283) Although electromagnetic fields are used for treatment after surgery, many patients prefer cell-based tissue regeneration procedures that do not require daily treatments.

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PMID:23281198 DOI:10.1002/term.1664

2015 Journal of tissue engineering and regenerative medicine

* Short-term evaluation of electromagnetic field pretreatment of adipose-derived stem cells to improve bone healing.

- An electromagnetic field is an effective stimulation tool because it promotes bone defect healing, albeit in an unknown way. Although electromagnetic fields are used for treatment after surgery, many patients prefer cell-based tissue regeneration procedures that do not require daily treatments. This study addressed the effects of an electromagnetic field on adipose-derived stem cells (ASCs) to investigate the feasibility of pretreatment to accelerate bone regeneration. After identifying a uniform electromagnetic field inside a solenoid coil, we observed that a 45 Hz electromagnetic field induced osteogenic marker expression via bone morphogenetic protein, transforming growth factor β, and Wnt signalling pathways based on microarray analyses. This electromagnetic field increased osteogenic gene expression, alkaline phosphate activity and nodule formation in vitro within 2 weeks, indicating that this pretreatment may provide osteogenic potential to ASCs on three-dimensional (3D) ceramic scaffolds. This pretreatment effect of an electromagnetic field resulted in significantly better bone regeneration in a mouse calvarial defect model over 4 weeks compared to that in the untreated group. This short-term evaluation showed that the electromagnetic field pretreatment may be a future therapeutic option for bone defect treatment.

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(1)247 on	(10)3 approach	(19)2 chemotherapy	(28)2 physical
(2)10 method	(11)3 hydrogels	(20)2 computer-tailored	(29)2 rehabilitation
(3)10 therapies	(12)3 information	(21)2 financing	(30)2 retrospective
(4)5 cross-sectional	(13)3 study	(22)2 learning	(31)2 scaffolds
(5)5 upon	(14)3 techniques	(23)2 methods	(32)2 strategy
(6)4 survey	(15)3 therapeutic	(24)2 modelling	(33)2 studies
(7)4 tissue	(16)2 NPWT	(25)2 morphometry	(34)2 telephone
(8)3 CRT	(17)2 RUTF	(26)2 nutrient	(35)2 vaccination
(9)3 anti-bullying	(18)2 and	(27)2 palliative

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--- WordNet output for based --- =>に基づき Overview of verb base The verb base has 3 senses (first 1 from tagged texts) 1. (75) establish, base, ground, found -- (use as a basis for; found on; "base a claim on some observation") 2. base -- (situate as a center of operations; "we will base this project in the new lab") 3. free-base, base -- (use (purified cocaine) by burning it and inhaling the fumes) Overview of adj based The adj based has 2 senses (first 2 from tagged texts) 1. (3) based -- (having a base; "firmly based ice") 2. (1) based -- (having a base of operations (often used as a combining form); "a locally based business"; "an Atlanta-based company"; "carrier-based planes") --- WordNet end ---