92) Giant congenital melanocytic nevi (GCMN) occur in 1:20,000 livebirths and are associated with increased risk of malignant transformation. |
PMID:23903082 DOI:10.1097/SAP.0b013e3182920c3d |
2015 Annals of plastic surgery |
* Giant congenital melanocytic nevus: report from 30 years of experience in a single department. |
- Giant congenital melanocytic nevi (GCMN) occur in 1:20,000 livebirths and are associated with increased risk of malignant transformation. The treatment of GCMN from 1981 to 2010 in a tertiary referral center was reviewed evaluating the modalities used, cosmetic results, associated complications, and malignant transformation. Of 35 patients, 25 underwent surgery. Curettage was most frequently used (64%) followed by excision and tissue expansion (20%). Six percent of the patients treated with curettage, and 78% of the patients who received excision surgery required more than 1 planned procedure, and 25% versus 44% required unplanned additional surgery, respectively. Complications were noted in 25% and 67% of the patients, respectively. Cosmetic result was satisfying in 76% of patients without difference between the groups. No malignant transformation was found during a mean follow-up of 11 years. Curettage is a gentle alternative to excision with a lower complication rate and good cosmetic outcome. |
(1)51 the | (16)4 significantly | (31)2 being | (46)2 less |
(2)31 a | (17)3 FIQ | (32)2 diabetes | (47)2 many |
(3)12 increased | (18)3 cancer | (33)2 different | (48)2 maternal |
(4)12 lower | (19)3 chronic | (34)2 early | (49)2 nephrolithiasis |
(5)9 higher | (20)3 more | (35)2 excessive | (50)2 normal |
(6)8 an | (21)3 other | (36)2 faster | (51)2 parenchymal |
(7)7 decreased | (22)3 perceived | (37)2 female | (52)2 physical |
(8)6 poor | (23)3 shorter | (38)2 gene | (53)2 positive |
(9)5 both | (24)3 smoking | (39)2 genetic | (54)2 reductions |
(10)5 greater | (25)3 specific | (40)2 good | (55)2 stress |
(11)4 adverse | (26)2 JS | (41)2 having | (56)2 them |
(12)4 negative | (27)2 SWD | (42)2 high | (57)2 this |
(13)4 poorer | (28)2 alterations | (43)2 implementation | (58)2 undernutrition |
(14)4 reduced | (29)2 altered | (44)2 improvements | (59)2 very |
(15)4 significant | (30)2 any | (45)2 internalizing |
add keyword