ELIZA

return kwic search for activity out of >500 occurrences
475194 occurrences (No.33 in the rank) during 5 years in the PubMed. [no cache] 500 found

195) Our results showed the presence of Xepac transcripts at all stages of oogenesis and we demonstrated that a cAMP analogue that exclusively activates Xepac, 8-CPT, was able to rescue the endocytic activity in oocytes with uncoupled gap junctions.

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PMID:23890344 DOI:10.1017/S0967199413000324

2015 Zygote (Cambridge, England)

* Xepac protein and IP3/Ca2+ pathway implication during Xenopus laevis vitellogenesis.

- The objective of this study was to elucidate the signalling pathways initiated by cAMP once inside the Xenopus laevis oocyte, where it triggers and maintains vitellogenin endocytic uptake. Our results showed the presence of Xepac transcripts at all stages of oogenesis and we demonstrated that a cAMP analogue that exclusively activates Xepac, 8-CPT, was able to rescue the endocytic activity in oocytes with uncoupled gap junctions. Inhibition experiments for the IP3/Ca2+ signalling pathway showed either a complete inhibition or a significant reduction of the vitellogenic process. These results were confirmed with the rescue capability of the A-23187 ionophore in those oocyte batches in which the IP3/Ca2+ pathway was inhibited. Taking our findings into account, we propose that the cAMP molecule binds Xepac protein enabling it to activate the IP3/Ca2+ pathway, which is necessary to start and maintain X. laevis vitellogenin uptake.

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(1)70 of	(13)6 patterns	(25)3 but	(37)2 functional
(2)54 null	(14)5 may	(26)3 changes	(38)2 increased
(3)49 and	(15)5 using	(27)3 for	(39)2 induces
(4)45 in	(16)5 with	(28)3 measured	(40)2 level
(5)17 was	(17)4 at	(29)3 through	(41)2 or
(6)11 against	(18)4 levels	(30)2 Questionnaire	(42)2 over
(7)10 during	(19)4 on	(31)2 after	(43)2 promotion
(8)9 (PA)	(20)4 which	(32)2 between	(44)2 resumption
(9)8 is	(21)4 while	(33)2 calcium	(45)2 than
(10)7 to	(22)3 among	(34)2 compared	(46)2 that
(11)7 were	(23)3 are	(35)2 decreased	(47)2 via
(12)6 by	(24)3 as	(36)2 diary	(48)2 when

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--- WordNet output for activity --- =>活動, 活躍, 働き, 動き, 活気 Overview of noun activity The noun activity has 6 senses (first 3 from tagged texts) 1. (43) activity -- (any specific behavior; "they avoided all recreational activity") 2. (36) action, activity, activeness -- (the state of being active; "his sphere of activity"; "he is out of action") 3. (13) bodily process, body process, bodily function, activity -- (an organic process that takes place in the body; "respiratory activity") 4. activity -- ((chemistry) the capacity of a substance to take part in a chemical reaction; "catalytic activity") 5. natural process, natural action, action, activity -- (a process existing in or produced by nature (rather than by the intent of human beings); "the action of natural forces"; "volcanic activity") 6. activeness, activity -- (the trait of being active; moving or acting rapidly and energetically; "the level of activity declines with age") --- WordNet end ---